AK4

Gene Symbol AK4
Entrez Gene 205
Alt Symbol AK 4, AK3, AK3L1, AK3L2
Species Human
Gene Type protein-coding
Description adenylate kinase 4
Other Description AK 4|ATP-AMP transphosphorylase|GTP:AMP phosphotransferase AK4, mitochondrial|adenylate kinase 3-like 1|adenylate kinase 4, mitochondrial|adenylate kinase isoenzyme 4, mitochondrial|mitochondrial adenylate kinase-3|nucleoside-triphosphate-adenylate kinase
Swissprots Q6NXQ5 P27144 Q6IBH4 D3DQ62 B2R927 Q8IUU9
Accessions CCE45535 EAX06538 EAX06540 EAX06544 P27144 AK025926 AK026966 AK309057 AK313611 BAG36374 BC016180 AAH16180 BC040224 AAH40224 BC066944 AAH66944 BC136886 AAI36887 BC136887 AAI36888 BC146653 AAI46654 BC148270 AAI48271 BF205061 BG703687 BM763432 BU164554 CR456830 CAG33111 DB061266 DQ892294 ABM83220 DQ895494 ABM86420 DR003868 X60673 CAA43088 NM_001005353 NP_001005353 NM_013410 NP_037542 NM_203464 NP_982289
Function Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000255|HAMAP-Rule:MF_03170, ECO:0000269|PubMed:19073142, ECO:0000269|PubMed:19766732, ECO:0000269|PubMed:23416111}.
Subcellular Location Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03170, ECO:0000269|PubMed:11485571, ECO:0000269|PubMed:19766732}.
Tissue Specificity Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain. {ECO:0000269|PubMed:11485571}.
Top Pathways Purine metabolism

AK4 (A-9) - sc-271161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AK4 (A-9): sc-271161. Western blot analysis of AK4 expression in non-transfected 293T: sc-117752 (A), human AK4 transfected 293T: sc-112661 (B) and Hep G2 (C) whole cell lysates.

AK4 (G-3) - sc-398661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AK4 (G-3): sc-398661. Western blot analysis of AK4 expression in Hep G2 (A), HeLa (B), Raji (C), A-431 (D) and MCF7 (E) whole cell lysates.

AK4 (H-59) - sc-366012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AK4 (H-59): sc-366012. Western blot analysis of AK4 expression in non-transfected 293T: sc-117752 (A), human AK4 transfected 293T: sc-112661 (B), Hep G2 (C), Raji (D) and A-431 (E) whole cell lysates.

AK4 (N-20) - sc-17627 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AK4 (N-20): sc-17627. Western blot analysis of AK4 expression in non-transfected 293T: sc-117752 (A), human AK4 transfected 293T: sc-114318 (B) and Hep G2 (C) whole cell lysates.

AK3/4 (SJB3-36) - sc-53912 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
AK3/4 (SJB3-36): sc-53912. Western blot analysis of AK3/4 expression in Hep G2 (A), A-673 (B), Caki-1 (C), HeLa (D), Jurkat (E) and HEL 92.1.7 (F) whole cell lysates.

Anti-AK3L1 antibody - ab196792 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AK3L1 antibody (ab196792) at 1/500 dilutionLane 1 : HepG2 cell extractLane 2 : Raji cell extractLane 3 : HeLa cell extractLane 4 : SW480 cell extractLane 5 : mouse liver cell extractLane 6 : mouse kidney cell extract

Anti-AK3L1 antibody - ab124393 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AK3L1 antibody (ab124393) at 1/500 dilutionLane 1 : Fetal kidneyLane 2 : Fetal liverLane 3 : HeLa

Anti-AK3L1 antibody - ab191268 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AK3L1 antibody (ab191268) at 1/1000 dilutionLane 1 : A431 cell line lysateLane 2 : HeLa cell line lysateLane 3 : HepG2 cell line lysateLane 4 : MCF7 cell line lysateLane 5 : Raji cell line lysateLane 6 : Mouse kidney tissue lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L (HRP) at 1/5000 dilution

Anti-AK3L1 antibody - ab96384 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-AK3L1 antibody (ab96384) at 1/500 dilution + liver tissue lysate at 50 µg

Anti-AK3L1 antibody [3E1] - ab119068 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E1
All lanes : Anti-AK3L1 antibody [3E1] (ab119068) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY AK3L1 cDNALysates/proteins at 5 µg per lane.

Anti-AK3L1 antibody [EPR7678] - ab131327 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7678
All lanes : Anti-AK3L1 antibody [EPR7678] (ab131327) at 1/1000 dilutionLane 1 : MCF-7 cell lysateLane 2 : HepG2 cell lysateLane 3 : Raji cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-AK3L1 antibody [EPR7679] - ab156880 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7679
Immunofluorescence of AK3L1 in A431 cells using ab156880 antibody at a dilution of 1/50.

Anti-AK4 / Adenylate Kinase 4 Antibody (clone 5E7) - LS-C172975 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5E7
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-AK4 mouse monoclonal antibody.

Anti-AK4 / Adenylate Kinase 4 Antibody (N-Terminus) IHC-plus™ - LS-B11482 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-AK4 / Adenylate Kinase 4 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-AK4 / Adenylate Kinase 4 Antibody (clone 2B12) - LS-C173184 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B12
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-AK4 mouse monoclonal antibody.

Anti-AK4 / Adenylate Kinase 4 Antibody (aa119-153) - LS-C344216 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded H.heart section using AK4 Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Anti-AK4 / Adenylate Kinase 4 Antibody (clone 3B1) - LS-C173011 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3B1
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-AK4 mouse monoclonal antibody.

Anti-AK4 / Adenylate Kinase 4 Antibody (aa126-175) - LS-C31854 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-AK4 / Adenylate Kinase 4 Antibody (aa23-53) - LS-C101252 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-AK3 antibody in mouse kidney tissue lysate (35 ug/lane). AK3(arrow) was detected using the purified antibody.

Anti-AK4 / Adenylate Kinase 4 Antibody - LS-C306165 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AK4 / Adenylate Kinase 4 Antibody (aa38-222) - LS-C178882 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AK4 / Adenylate Kinase 4 Antibody (clone 5B10) - LS-C172764 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5B10
Anti-AK4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AK4.

Anti-AK4 / Adenylate Kinase 4 Antibody - LS-C192690 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of MCF7 cell lines, using AK4 antibody.

Anti-AK4 / Adenylate Kinase 4 Antibody (clone 3A9) - LS-C173220 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AK4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AK4.

Anti-AK4 / Adenylate Kinase 4 Antibody (Internal, clone EPR7678) - LS-C154564 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7678
IHC of paraffin-embedded human liver tissue using anti-AK4 antibody.
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