AK4

Gene Symbol	AK4
Entrez Gene	205
Alt Symbol	AK 4, AK3, AK3L1, AK3L2
Species	Human
Gene Type	protein-coding
Description	adenylate kinase 4
Other Description	AK 4|ATP-AMP transphosphorylase|GTP:AMP phosphotransferase AK4, mitochondrial|adenylate kinase 3-like 1|adenylate kinase 4, mitochondrial|adenylate kinase isoenzyme 4, mitochondrial|mitochondrial adenylate kinase-3|nucleoside-triphosphate-adenylate kinase
Swissprots	Q6NXQ5 P27144 Q6IBH4 D3DQ62 B2R927 Q8IUU9
Accessions	CCE45535 EAX06538 EAX06540 EAX06544 P27144 AK025926 AK026966 AK309057 AK313611 BAG36374 BC016180 AAH16180 BC040224 AAH40224 BC066944 AAH66944 BC136886 AAI36887 BC136887 AAI36888 BC146653 AAI46654 BC148270 AAI48271 BF205061 BG703687 BM763432 BU164554 CR456830 CAG33111 DB061266 DQ892294 ABM83220 DQ895494 ABM86420 DR003868 X60673 CAA43088 NM_001005353 NP_001005353 NM_013410 NP_037542 NM_203464 NP_982289
Function	Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000255|HAMAP-Rule:MF_03170, ECO:0000269|PubMed:19073142, ECO:0000269|PubMed:19766732, ECO:0000269|PubMed:23416111}.
Subcellular Location	Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03170, ECO:0000269|PubMed:11485571, ECO:0000269|PubMed:19766732}.
Tissue Specificity	Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain. {ECO:0000269|PubMed:11485571}.
Top Pathways	Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AK3L1 full length protein - ab103301 from Abcam Category Protein Prices $235.00, $866.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human AK3L1 full length protein - ab117690 from Abcam Category Protein Prices $188.00 Sizes 5 µg Source E. coli Species Human

AK4 / Adenylate Kinase 4 Antibody Blocking Peptide - LS-E9514 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AK4 / Adenylate Kinase 4 Antibody Blocking Peptide - LS-E9515 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AK4 / Adenylate Kinase 4 Antibody Blocking Peptide - LS-E15245 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AK3L1 Partial Recombinant Protein - H00000205-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

AK3L1 Recombinant Protein - H00000205-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

AK3L1 Recombinant Protein - H00000205-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg

Recombinant Human AK3L1 Protein - NBP1-72279 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E. coli Species Human

AK3-Antibody-C-term-T208-Blocking-Peptide - BP8132d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AK3-Antibody-N-term-F210-Blocking-Peptide - BP8132c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AK3-Antibody-C-term-H38-Blocking-Peptide - BP8132b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AK3L1 Protein (OPPA01705) - OPPA01705 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human AK4 protein - orb138145 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Human AK4 protein - orb167872 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

Adenylate kinase 4 / AK4 (1-223, His-tag) - AR09820PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Adenylate kinase 4 / AK4 (1-223, His-tag) - AR09820PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Adenylate kinase 4 (AK4) - H00000205-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Adenylate kinase 4 (AK4) - H00000205-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Adenylate Kinase-3 Like 1, Human Recombinant - 228-10038-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human AK3L1 - 228-10038-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human AK3L1 - 228-10038-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

Adenylate Kinase 4, Human Recombinant - 228-12710-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Adenylate Kinase 4 - 228-12710-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Adenylate Kinase 4 - 228-12710-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

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