AK4

Gene Symbol AK4
Entrez Gene 205
Alt Symbol AK 4, AK3, AK3L1, AK3L2
Species Human
Gene Type protein-coding
Description adenylate kinase 4
Other Description AK 4|ATP-AMP transphosphorylase|GTP:AMP phosphotransferase AK4, mitochondrial|adenylate kinase 3-like 1|adenylate kinase 4, mitochondrial|adenylate kinase isoenzyme 4, mitochondrial|mitochondrial adenylate kinase-3|nucleoside-triphosphate-adenylate kinase
Swissprots Q6NXQ5 P27144 Q6IBH4 D3DQ62 B2R927 Q8IUU9
Accessions CCE45535 EAX06538 EAX06540 EAX06544 P27144 AK025926 AK026966 AK309057 AK313611 BAG36374 BC016180 AAH16180 BC040224 AAH40224 BC066944 AAH66944 BC136886 AAI36887 BC136887 AAI36888 BC146653 AAI46654 BC148270 AAI48271 BF205061 BG703687 BM763432 BU164554 CR456830 CAG33111 DB061266 DQ892294 ABM83220 DQ895494 ABM86420 DR003868 X60673 CAA43088 NM_001005353 NP_001005353 NM_013410 NP_037542 NM_203464 NP_982289
Function Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000255|HAMAP-Rule:MF_03170, ECO:0000269|PubMed:19073142, ECO:0000269|PubMed:19766732, ECO:0000269|PubMed:23416111}.
Subcellular Location Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03170, ECO:0000269|PubMed:11485571, ECO:0000269|PubMed:19766732}.
Tissue Specificity Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain. {ECO:0000269|PubMed:11485571}.
Top Pathways Purine metabolism

AK4 CRISPR/Cas9 KO Plasmid (h) - sc-416951 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 HDR Plasmid (h) - sc-416951-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 Double Nickase Plasmid (h) - sc-416951-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 Double Nickase Plasmid (h2) - sc-416951-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 CRISPR Activation Plasmid (h) - sc-416951-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 CRISPR Activation Plasmid (h2) - sc-416951-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 Lentiviral Activation Particles (h) - sc-416951-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 Lentiviral Activation Particles (h2) - sc-416951-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AK4 siRNA (h) - sc-38908 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AK4 shRNA Plasmid (h) - sc-38908-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AK4 shRNA (h) Lentiviral Particles - sc-38908-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AK3L1 RNAi - H00000205-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU114081 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0084 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0083 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0082 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2997 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2997 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AK4 siRNA (Human) - CRH0142 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AK3L1 RNAi - H00000205-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AK3L1 RNAi - H00000205-R09 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AK4 - MBS8240029 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human AK4 siRNA - orb260644 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AK4 shRNA Plasmid (Human) - CHH0142 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AK4 miRNA 3'UTR clone - MiUTR3H-00073 from Creative biogene

Species Reactivities Human
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