AK4

Gene Symbol	AK4
Entrez Gene	205
Alt Symbol	AK 4, AK3, AK3L1, AK3L2
Species	Human
Gene Type	protein-coding
Description	adenylate kinase 4
Other Description	AK 4|ATP-AMP transphosphorylase|GTP:AMP phosphotransferase AK4, mitochondrial|adenylate kinase 3-like 1|adenylate kinase 4, mitochondrial|adenylate kinase isoenzyme 4, mitochondrial|mitochondrial adenylate kinase-3|nucleoside-triphosphate-adenylate kinase
Swissprots	Q6NXQ5 P27144 Q6IBH4 D3DQ62 B2R927 Q8IUU9
Accessions	CCE45535 EAX06538 EAX06540 EAX06544 P27144 AK025926 AK026966 AK309057 AK313611 BAG36374 BC016180 AAH16180 BC040224 AAH40224 BC066944 AAH66944 BC136886 AAI36887 BC136887 AAI36888 BC146653 AAI46654 BC148270 AAI48271 BF205061 BG703687 BM763432 BU164554 CR456830 CAG33111 DB061266 DQ892294 ABM83220 DQ895494 ABM86420 DR003868 X60673 CAA43088 NM_001005353 NP_001005353 NM_013410 NP_037542 NM_203464 NP_982289
Function	Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000255|HAMAP-Rule:MF_03170, ECO:0000269|PubMed:19073142, ECO:0000269|PubMed:19766732, ECO:0000269|PubMed:23416111}.
Subcellular Location	Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03170, ECO:0000269|PubMed:11485571, ECO:0000269|PubMed:19766732}.
Tissue Specificity	Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain. {ECO:0000269|PubMed:11485571}.
Top Pathways	Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AK3L1-Over-expression-Lysate - LY10643a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

AK4 overexpression lysate - LY402259 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

AK4 overexpression lysate - LY404279 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

AK4 overexpression lysate - LY423694 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

AK4 overexpression lysate - LY430929 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

AK3L1 293 Cell Lysate - 401984 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

AK3L1 293 Cell Lysate - 409982 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

AK3L1 Overexpression Lysate (Native) - NBL1-07421 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

AK3L1 Overexpression Lysate (Native) - NBL1-07420 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

AK3L1 Overexpression Lysate (Native) - NBP2-04550 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

AK4 (h): 293T Lysate - sc-112661 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

AK4 (h2): 293T Lysate - sc-114318 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

AK4 Over-expression Lysate Product - GWB-C3E21A from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

AK4 Over-expression Lysate Product - GWB-4FADC0 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human AK4 / Adenylate Kinase 4 / AK3L1 Insect Cell Lysate (WB positive control) - 12406-HNCBL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human AK4 / Adenylate Kinase 4 / AK3L1 Insect Cell Lysate (WB positive control) - 12406-H20BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human AK4 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175288 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human AK4 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175022 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

AK3L1 Overexpression Lysate (Denatured) - H00000205-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human AK4 Knockdown Stable Cell Line - CSC-DC000426 from Creative biogene Category Cell Line Species Human

Human AK4 Knockout Cell Line-HeLa - CSC-RT1746 from Creative biogene Category Cell Line Species Human

AK4 KO Cell Lysate-HeLa - CLKO-1593 from Creative biogene Category Cell Lysate

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