GCNT1

Gene Symbol GCNT1
Entrez Gene 2650
Alt Symbol C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2
Species Human
Gene Type protein-coding
Description glucosaminyl (N-acetyl) transferase 1, core 2
Other Description beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase|beta-1,6-N-acetylglucosaminyltransferase|core 2 GnT|core 2 beta-1,6-N-acetylglucosaminyltransferase I|core 2 beta1,6 N-acetylglucosaminyltransferase-I|core 2 branching enzyme|core 2-branching enzyme|core2-GlcNAc-transferase|glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Swissprots Q6DJZ4 Q02742
Accessions AAA96661 EAW62580 Q02742 AI445628 AJ420416 AK313343 BAG36146 AL832647 CAD89956 AY196293 AY196294 AY196295 AY196296 AY196297 BC074885 AAH74885 BC074886 AAH74886 BC109101 AAI09102 BC109102 AAI09103 BP359964 DA479942 M97347 AAA35919 XM_006717052 XP_006717115 NM_001097633 NP_001091102 NM_001097634 NP_001091103 NM_001097635 NP_001091104 NM_001097636 NP_001091105 NM_001490 NP_001481
Function Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes. {ECO:0000269|PubMed:23027862}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:23027862}; Single-pass type II membrane protein {ECO:0000269|PubMed:23027862}. Note=Also detected in the trans-Golgi network.
Tissue Specificity Highly expressed in activated T-lymphocytes and myeloid cells.
Top Pathways Mucin type O-Glycan biosynthesis

GCNT1 (H-43) - sc-134711 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GCNT1 (H-43): sc-134711. Western blot analysis of GCNT1 expression in mouse kidney tissue extract.

GCNT1 (I-19) - sc-130143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
GCNT1 (I-19): sc-130143. Western blot analysis of GCNT1 expression in mouse kidney tissue extract.

Anti-GCNT1 antibody - ab102665 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GCNT1 antibody (ab102665) at 1/500 dilution + Human Pancreas Tissue Lysate at 50 µg

Anti-GCNT1 antibody - ab38858 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GCNT1 antibody (ab38858) + CEM cell lysate at 35 µg

Anti-GCNT1 / C2GNT Antibody (aa63-91, AP) - LS-C257613 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (aa63-91, APC) - LS-C257614 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (aa63-91, Biotin) - LS-C257616 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (aa63-91, FITC) - LS-C257617 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (aa63-91, Azide-free, HRP) - LS-C257618 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (aa63-91, PE) - LS-C257619 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (C-Terminus, APC) - LS-C277632 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (C-Terminus, AP) - LS-C277633 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (C-Terminus, Biotin) - LS-C277634 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (Internal, AP) - LS-C277637 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (C-Terminus, Azide-free, HRP) - LS-C277635 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (Internal, APC) - LS-C277638 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (C-Terminus, PE) - LS-C277639 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (C-Terminus, FITC) - LS-C277636 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (Internal, Biotin) - LS-C277640 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (Internal, FITC) - LS-C277641 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (aa63-91) - LS-C159719 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GCNT1 Antibody western blot of T47D cell line lysates (35 ug/lane). The GCNT1 antibody detected the GCNT1 protein (arrow).

Anti-GCNT1 / C2GNT Antibody (Internal, Azide-free, HRP) - LS-C277642 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (Internal, PE) - LS-C277643 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCNT1 / C2GNT Antibody (aa88-117) - LS-C99699 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-GCNT1 / C2GNT Antibody - LS-C307659 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Search more