GCNT1

Gene Symbol GCNT1
Entrez Gene 2650
Alt Symbol C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2
Species Human
Gene Type protein-coding
Description glucosaminyl (N-acetyl) transferase 1, core 2
Other Description beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase|beta-1,6-N-acetylglucosaminyltransferase|core 2 GnT|core 2 beta-1,6-N-acetylglucosaminyltransferase I|core 2 beta1,6 N-acetylglucosaminyltransferase-I|core 2 branching enzyme|core 2-branching enzyme|core2-GlcNAc-transferase|glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Swissprots Q6DJZ4 Q02742
Accessions AAA96661 EAW62580 Q02742 AI445628 AJ420416 AK313343 BAG36146 AL832647 CAD89956 AY196293 AY196294 AY196295 AY196296 AY196297 BC074885 AAH74885 BC074886 AAH74886 BC109101 AAI09102 BC109102 AAI09103 BP359964 DA479942 M97347 AAA35919 XM_006717052 XP_006717115 NM_001097633 NP_001091102 NM_001097634 NP_001091103 NM_001097635 NP_001091104 NM_001097636 NP_001091105 NM_001490 NP_001481
Function Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes. {ECO:0000269|PubMed:23027862}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:23027862}; Single-pass type II membrane protein {ECO:0000269|PubMed:23027862}. Note=Also detected in the trans-Golgi network.
Tissue Specificity Highly expressed in activated T-lymphocytes and myeloid cells.
Top Pathways Mucin type O-Glycan biosynthesis

GCNT1 293T Cell Transient Overexpression Lysate(Denatured) - H00002650-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

GCNT1 293 Cell Lysate - 409324 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Overexpression Lysate (Denatured) - H00002650-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
GCNT1 transfected lysate.

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Overexpression Lysate (Native) - NBL1-11014 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: GCNT1 Overexpression Lysate (Adult Normal) [NBL1-11014] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GCNT1.

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Overexpression Lysate (Native) - NBP2-08274 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Overexpression Lysate (Native) - NBP2-08273 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Overexpression Lysate (Native) - NBP2-08272 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: GCNT1 Overexpression Lysate (Adult Normal) [NBP2-08272] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GCNT1.

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Overexpression Lysate (Native) - NBP2-08271 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: GCNT1 Overexpression Lysate (Adult Normal) [NBP2-08271] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GCNT1.

GCNT1 Over-expression Lysate Product - GWB-4E13E5 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human GCNT1 Knockdown Stable Cell Line - CSC-DC006170 from Creative biogene

Category Cell Line
Species Human
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