GCNT1

Gene Symbol GCNT1
Entrez Gene 2650
Alt Symbol C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2
Species Human
Gene Type protein-coding
Description glucosaminyl (N-acetyl) transferase 1, core 2
Other Description beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase|beta-1,6-N-acetylglucosaminyltransferase|core 2 GnT|core 2 beta-1,6-N-acetylglucosaminyltransferase I|core 2 beta1,6 N-acetylglucosaminyltransferase-I|core 2 branching enzyme|core 2-branching enzyme|core2-GlcNAc-transferase|glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Swissprots Q6DJZ4 Q02742
Accessions AAA96661 EAW62580 Q02742 AI445628 AJ420416 AK313343 BAG36146 AL832647 CAD89956 AY196293 AY196294 AY196295 AY196296 AY196297 BC074885 AAH74885 BC074886 AAH74886 BC109101 AAI09102 BC109102 AAI09103 BP359964 DA479942 M97347 AAA35919 XM_006717052 XP_006717115 NM_001097633 NP_001091102 NM_001097634 NP_001091103 NM_001097635 NP_001091104 NM_001097636 NP_001091105 NM_001490 NP_001481
Function Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes. {ECO:0000269|PubMed:23027862}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:23027862}; Single-pass type II membrane protein {ECO:0000269|PubMed:23027862}. Note=Also detected in the trans-Golgi network.
Tissue Specificity Highly expressed in activated T-lymphocytes and myeloid cells.
Top Pathways Mucin type O-Glycan biosynthesis

GCNT1 CRISPR/Cas9 KO Plasmid (h) - sc-410791 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 HDR Plasmid (h) - sc-410791-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 Double Nickase Plasmid (h) - sc-410791-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 Double Nickase Plasmid (h2) - sc-410791-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 CRISPR Activation Plasmid (h) - sc-410791-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 CRISPR Activation Plasmid (h2) - sc-410791-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 Lentiviral Activation Particles (h) - sc-410791-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 Lentiviral Activation Particles (h2) - sc-410791-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCNT1 siRNA (h) - sc-92945 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GCNT1 shRNA Plasmid (h) - sc-92945-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GCNT1 shRNA (h) Lentiviral Particles - sc-92945-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU129421 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9196 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9196 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GCNT1 siRNA (Human) - CRH1764 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GCNT1 - MBS8221892 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GCNT1 (NM_001490.4) - SHH300106 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GCNT1(NM_001490.4) - SHH080237 from Creative biogene

Category siRNA
Species Reactivities Human

Human GCNT1 siRNA - orb262266 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GCNT1 shRNA Plasmid (Human) - CHH1764 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GCNT1 miRNA 3'UTR clone - MiUTR1H-03990 from Creative biogene

Species Reactivities Human

GCNT1 miRNA 3'UTR clone - MiUTR4H-TG03758 from Creative biogene

Species Reactivities Human
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