GCNT1

Gene Symbol	GCNT1
Entrez Gene	2650
Alt Symbol	C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2
Species	Human
Gene Type	protein-coding
Description	glucosaminyl (N-acetyl) transferase 1, core 2
Other Description	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase|beta-1,6-N-acetylglucosaminyltransferase|core 2 GnT|core 2 beta-1,6-N-acetylglucosaminyltransferase I|core 2 beta1,6 N-acetylglucosaminyltransferase-I|core 2 branching enzyme|core 2-branching enzyme|core2-GlcNAc-transferase|glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Swissprots	Q6DJZ4 Q02742
Accessions	AAA96661 EAW62580 Q02742 AI445628 AJ420416 AK313343 BAG36146 AL832647 CAD89956 AY196293 AY196294 AY196295 AY196296 AY196297 BC074885 AAH74885 BC074886 AAH74886 BC109101 AAI09102 BC109102 AAI09103 BP359964 DA479942 M97347 AAA35919 XM_006717052 XP_006717115 NM_001097633 NP_001091102 NM_001097634 NP_001091103 NM_001097635 NP_001091104 NM_001097636 NP_001091105 NM_001490 NP_001481
Function	Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes. {ECO:0000269|PubMed:23027862}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:23027862}; Single-pass type II membrane protein {ECO:0000269|PubMed:23027862}. Note=Also detected in the trans-Golgi network.
Tissue Specificity	Highly expressed in activated T-lymphocytes and myeloid cells.
Top Pathways	Mucin type O-Glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GCNT1 full length protein - ab114895 from Abcam Category Protein Source Wheat germ Species Human

GCNT1 / C2GNT Antibody Blocking Peptide - LS-E4777 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GCNT1 / C2GNT Antibody Blocking Peptide - LS-E6949 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GCNT1 / C2GNT Antibody Blocking Peptide - LS-E6950 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Protein - H00002650-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Peptide - P1079 from Novus Biologicals Category Peptide Species Human

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Peptide - P1078 from Novus Biologicals Category Peptide Species Human

GCNT1-Antibody-Center-Blocking-Peptide - BP17151c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCNT1-Antibody-C-term-Blocking-Peptide - BP2404b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCNT1-Antibody-Center-Blocking-Peptide - BP2404a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human GCNT1, CF - 7248-GT-020 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Arg33-His428, with an N-terminal CD33 signal sequence and a C-terminal 6-His tag

GCNT1 / NACGT2 - H00002650-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GCNT1 / NACGT2 - H00002650-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GCNT1 fusion protein - ag12264 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Glucosaminyl (N-acetyl) Transferase 1, Core 2, His-tagged - GCNT1-617H from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived.

Recombinant Human GCNT1 - GCNT1-27452TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human GCNT1, GST-tagged - GCNT1-13198H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human GCNT1 Protein, CF - 7248-GT from R&D Systems Category Protein Prices $359.00 Sizes 20 µg Source Mouse myeloma cell line, NS0-derived Arg33-His428, with an N-terminal CD33 signal sequence and a C-terminal 6-His tag Species Human

Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Recombinant Protein Antigen - NBP1-86809PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

GCNT1 Peptide, Human - M34GP06170H from Creative Peptides Category Peptide Source Synthetic. Species Human

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