RGS2

Gene Symbol RGS2
Entrez Gene 5997
Alt Symbol G0S8
Species Human
Gene Type protein-coding
Description regulator of G-protein signaling 2
Other Description G0 to G1 switch regulatory 8, 24kD|G0/G1 switch regulatory protein 8|cell growth-inhibiting gene 31 protein|cell growth-inhibiting protein 31|regulator of G-protein signaling 2, 24kDa
Swissprots Q6I9U5 P41220
Accessions AAA20680 EAW91231 EAW91232 P41220 AF493926 AAM12640 AK313668 BAG36420 AY971351 AAY40361 BC007049 AAH07049 BC042755 AAH42755 BC044742 BI912389 BT007065 AAP35728 CD700013 CR457410 CAG33691 DQ893178 ABM84104 DQ896478 ABM87477 L13463 AAC37587 NM_002923 NP_002914
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein. {ECO:0000269|PubMed:11278586, ECO:0000269|PubMed:17901199, ECO:0000269|PubMed:19736320, ECO:0000269|PubMed:7643615}.
Subcellular Location Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus.
Tissue Specificity Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL). {ECO:0000269|PubMed:7643615}.
Top Pathways Oxytocin signaling pathway, cGMP-PKG signaling pathway

RGS2 (H-90) - sc-9103 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RGS2 (H-90): sc-9103. Western blot analysis of RGS2 expression in IMR-32 nuclear extract.

RGS2 (C-18) - sc-7678 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RGS2 (N-16) - sc-9933 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RGS2 (BC-43) - sc-100761 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
RGS2 (BC-43): sc-100761. Western blot analysis of RGS2 expression in MCF7 whole cell lysate.

Anti-RGS2 antibody - ab36561 from Abcam

Prices $394.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RGS2 antibody (ab36561) at 1 µg/ml + Brain (Human) Tissue Lysate - adult normal tissue (ab29466) at 10 µgSecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-RGS2 antibody - ab9963 from Abcam

Prices $372.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 antibody - ab115684 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115684 at 20µg/ml staining RGS2 in Formalin-fixed, Paraffin-embedded Human brain (cortex) tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-RGS2 antibody - ab155762 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RGS2 antibody (ab155762) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-RGS2 antibody - ab14069 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-RGS2 antibody - ab57922 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-RGS2 Antibody (aa1-211) - LS-C90995 from LifeSpan Bioscience

Prices $650.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-RGS2 Antibody (aa4-32, APC) - LS-C268183 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 Antibody (aa4-32, AP) - LS-C268184 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 Antibody (aa4-32, Biotin) - LS-C268185 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 Antibody (aa4-32, FITC) - LS-C285040 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 Antibody (aa4-32, Azide-free, HRP) - LS-C285041 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 Antibody (aa101-150) - LS-C31982 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SP2/0 Cell Lysate

Anti-RGS2 Antibody (aa4-32, PE) - LS-C285042 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 Antibody (aa4-32) - LS-C324651 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RGS2 Antibody (aa111-211, Azide-free) - LS-C328513 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RGS2 Antibody - LS-C192893 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of human brain cell lines, using RGS2 antibody.

Anti-RGS2 Antibody (aa4-32) - LS-C155991 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RGS2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The RGS2 antibody detected the RGS2 protein (arrow).

Anti-RGS2 Antibody (clone 4C4) - LS-C104902 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C4
RGS2 monoclonal antibody (M01), clone 4C4 Western blot of RGS2 expression in MCF-7.

Anti-RGS2 Antibody - LS-C331692 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of human brain cell lines, using RGS2 antibody.

Anti-RGS2 Antibody (aa1-50) IHC-plus™ - LS-B122 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RGS2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B122 concentration 20 ug/ml.
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