RGS2

Gene Symbol	RGS2
Entrez Gene	5997
Alt Symbol	G0S8
Species	Human
Gene Type	protein-coding
Description	regulator of G-protein signaling 2
Other Description	G0 to G1 switch regulatory 8, 24kD|G0/G1 switch regulatory protein 8|cell growth-inhibiting gene 31 protein|cell growth-inhibiting protein 31|regulator of G-protein signaling 2, 24kDa
Swissprots	Q6I9U5 P41220
Accessions	AAA20680 EAW91231 EAW91232 P41220 AF493926 AAM12640 AK313668 BAG36420 AY971351 AAY40361 BC007049 AAH07049 BC042755 AAH42755 BC044742 BI912389 BT007065 AAP35728 CD700013 CR457410 CAG33691 DQ893178 ABM84104 DQ896478 ABM87477 L13463 AAC37587 NM_002923 NP_002914
Function	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein. {ECO:0000269|PubMed:11278586, ECO:0000269|PubMed:17901199, ECO:0000269|PubMed:19736320, ECO:0000269|PubMed:7643615}.
Subcellular Location	Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus.
Tissue Specificity	Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL). {ECO:0000269|PubMed:7643615}.
Top Pathways	Oxytocin signaling pathway, cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RGS2 Gene cDNA Clone - orb145042 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-RGS2-cDNA-Clone - DC02070 from Abgent, a WuXi AppTec company Prices $284.85 Sizes 10 µg Species Human Accession BC007049

RGS2 - MBS1277735 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC007049

Human RGS2 ORF Clone(NM_002923.3) - CDCL173616 from Creative Biomart Species Human Accession NM_002923.3

Human RGS2 Gene ORF cDNA clone in cloning vector - HG14010-G from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14010-CH from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14010-CM from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14010-NY from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14010-ACR from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14010-ANR from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14010-ANG from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid - HG14010-UT from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14010-CY from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14010-ACG from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14010-NH from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14010-NF from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14010-NM from Sino Biological Species Human

Human RGS2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14010-CF from Sino Biological Species Human

Human RGS2 ORF Clone (BC007049) - CDCS411044 from Creative biogene Species Human Accession P41220

Human RGS2 ORF clone (BC007049) - CDCB159474 from Creative biogene Species Human

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