RGS2

Gene Symbol	RGS2
Entrez Gene	5997
Alt Symbol	G0S8
Species	Human
Gene Type	protein-coding
Description	regulator of G-protein signaling 2
Other Description	G0 to G1 switch regulatory 8, 24kD|G0/G1 switch regulatory protein 8|cell growth-inhibiting gene 31 protein|cell growth-inhibiting protein 31|regulator of G-protein signaling 2, 24kDa
Swissprots	Q6I9U5 P41220
Accessions	AAA20680 EAW91231 EAW91232 P41220 AF493926 AAM12640 AK313668 BAG36420 AY971351 AAY40361 BC007049 AAH07049 BC042755 AAH42755 BC044742 BI912389 BT007065 AAP35728 CD700013 CR457410 CAG33691 DQ893178 ABM84104 DQ896478 ABM87477 L13463 AAC37587 NM_002923 NP_002914
Function	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein. {ECO:0000269|PubMed:11278586, ECO:0000269|PubMed:17901199, ECO:0000269|PubMed:19736320, ECO:0000269|PubMed:7643615}.
Subcellular Location	Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus.
Tissue Specificity	Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL). {ECO:0000269|PubMed:7643615}.
Top Pathways	Oxytocin signaling pathway, cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RGS2 full length protein - ab75338 from Abcam Category Protein Source E. coli Species Human

Human RGS2 full length protein - ab104636 from Abcam Category Protein Source E. coli Species Human

Human RGS2 full length protein - ab169917 from Abcam Category Protein Source E. coli Species Human

Human RGS2 full length protein - ab125783 from Abcam Category Protein Source E. coli Species Human

Human RGS2 peptide - ab36560 from Abcam Category Peptide

RGS2 Antibody Blocking Peptide - LS-E15763 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RGS2 Antibody Blocking Peptide - LS-E15764 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RGS2 Recombinant Protein - H00005997-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RGS2 Partial Recombinant Protein - H00005997-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human RGS2 Protein - NBP1-51045 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 10 µg, 50 µg Source E. coli Species Human

RGS2 Protein (OOPA00204) - OOPA00204 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 1 µg Source Escherichia Coli.

Human RGS2 protein - orb244494 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human RGS2 protein - orb169189 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 1 μg, 5 μg, 50 μg Source E. coli

RGS2 protein (His tag) - 80R-1733 from Fitzgerald Category Protein Prices $255.00 Sizes 10 µg Source E.coli

RGS2 (1-211, His-tag) - AR09915PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

RGS2 (1-211, His-tag) - AR09915PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

RGS2 - H00005997-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

RGS2 - H00005997-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RGS2 - H00005997-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RGS2 - H00005997-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RGS2, 1-211aa, Human, His tag, E.coli - 01-1796-2 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

RGS2 fusion protein - Ag1066 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Regulator of G-Protein Signaling 2 Protein - BP002416-PRO-182 from Syd Labs Category Protein Prices $160.00, $1,200.00 Sizes 5 µg, 50 µg Source E. coli-derived. Species Human

RGS2, 1-211aa, Recombinant Protein - GWB-P1063J from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 10 μg, 50 μg Source E.coli Species Human

RGS2 Human Protein - GWB-BSP609 from Genway Biotech Category Protein Prices $75.00, $165.00, $1,435.00 Sizes 1 μg, 5 μg, 50 μg Source Escherichia Coli. Species Human

Search more