RGS2

Gene Symbol RGS2
Entrez Gene 5997
Alt Symbol G0S8
Species Human
Gene Type protein-coding
Description regulator of G-protein signaling 2
Other Description G0 to G1 switch regulatory 8, 24kD|G0/G1 switch regulatory protein 8|cell growth-inhibiting gene 31 protein|cell growth-inhibiting protein 31|regulator of G-protein signaling 2, 24kDa
Swissprots Q6I9U5 P41220
Accessions AAA20680 EAW91231 EAW91232 P41220 AF493926 AAM12640 AK313668 BAG36420 AY971351 AAY40361 BC007049 AAH07049 BC042755 AAH42755 BC044742 BI912389 BT007065 AAP35728 CD700013 CR457410 CAG33691 DQ893178 ABM84104 DQ896478 ABM87477 L13463 AAC37587 NM_002923 NP_002914
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein. {ECO:0000269|PubMed:11278586, ECO:0000269|PubMed:17901199, ECO:0000269|PubMed:19736320, ECO:0000269|PubMed:7643615}.
Subcellular Location Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus.
Tissue Specificity Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL). {ECO:0000269|PubMed:7643615}.
Top Pathways Oxytocin signaling pathway, cGMP-PKG signaling pathway

RGS2 CRISPR/Cas9 KO Plasmid (h) - sc-418500 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 HDR Plasmid (h) - sc-418500-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 Double Nickase Plasmid (h) - sc-418500-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 Double Nickase Plasmid (h2) - sc-418500-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 CRISPR Activation Plasmid (h) - sc-418500-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 CRISPR Activation Plasmid (h2) - sc-418500-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 Lentiviral Activation Particles (h) - sc-418500-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 Lentiviral Activation Particles (h2) - sc-418500-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RGS2 siRNA (h) - sc-40659 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RGS2 shRNA Plasmid (h) - sc-40659-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RGS2 shRNA (h) Lentiviral Particles - sc-40659-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RGS2 RNAi - H00005997-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU155031 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18224 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18224 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06104 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06104

RGS2 siRNA (Human) - CRH4065 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RGS2 - MBS8227087 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RGS2 (NM_002923.3) - SHH394924 from Creative biogene

Category siRNA
Species Reactivities Human

Human RGS2 siRNA - orb264567 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RGS2 shRNA Plasmid (Human) - CHH4065 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RGS2 miRNA 3'UTR clone - MiUTR3H-03688 from Creative biogene

Species Reactivities Human
Search more