MATK

Gene Symbol	MATK
Entrez Gene	4145
Alt Symbol	CHK, CTK, HHYLTK, HYL, HYLTK, Lsk
Species	Human
Gene Type	protein-coding
Description	megakaryocyte-associated tyrosine kinase
Other Description	CSK homologous kinase|Csk-homologous kinase|Csk-type protein tyrosine kinase|HYL tyrosine kinase|hematopoietic consensus tyrosine-lacking kinase|hydroxyaryl-protein kinase|leukocyte carboxyl-terminal src kinase related|megakaryocyte-associated tyrosine-protein kinase|protein kinase HYL|tyrosine kinase MATK|tyrosine-protein kinase CTK|tyrosylprotein kinase
Swissprots	Q9NST8 B3KNZ9 P42679
Accessions	AAC60645 AAC62843 EAW69284 EAW69285 EAW69286 EAW69287 P42679 AB593100 BAJ84040 AK055395 BAG51511 AK225834 AK315646 BAG38013 AL137754 CAB70906 BC000114 AAH00114 BC003109 AAH03109 BG396388 BM925586 BQ109562 DA592994 L18974 AAA16703 S71669 AAB30995 X77278 CAA54493 XM_011528018 XP_011526320 XM_011528019 XP_011526321 NM_002378 NP_002369 NM_139354 NP_647611 NM_139355 NP_647612
Function	Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. {ECO:0000269|PubMed:9171348}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9171348}. Membrane {ECO:0000269|PubMed:9171348}. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
Tissue Specificity	Expressed in various myeloid cell lines, detected in brain and lung.
Top Pathways	Neurotrophin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Lsk/Ctk (32) - sc-136309 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Lsk/Ctk (H-1) - sc-271174 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Lsk/Ctk (H-87) - sc-48827 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Lsk (C-20) - sc-533 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-MATK antibody - ab37824 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-MATK antibody [9D7] - ab91198 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 9D7

Anti-MATK Antibody (Val157) - LS-C193181 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (aa477-505, AP) - LS-C262720 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (clone 2C5) - LS-C197654 from LifeSpan Bioscience Prices $355.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2C5

Anti-MATK Antibody (aa477-505, APC) - LS-C262721 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (aa477-505, Biotin) - LS-C262722 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (aa477-505, FITC) - LS-C262723 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (aa477-505, Azide-free, HRP) - LS-C262724 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (aa477-505, PE) - LS-C262725 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (N-Terminus, AP) - LS-C279269 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (N-Terminus, APC) - LS-C279270 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (N-Terminus, FITC) - LS-C279272 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (N-Terminus, Azide-free, HRP) - LS-C279273 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (N-Terminus, Biotin) - LS-C279271 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (aa476-505) - LS-C322871 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (clone 9D7) - LS-C108838 from LifeSpan Bioscience Prices $345.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 9D7

Anti-MATK Antibody (N-Terminus) - LS-C327842 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (aa1-30) - LS-C99384 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody - LS-C155320 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-MATK Antibody (C-Terminus) - LS-C345253 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

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