MATK

Gene Symbol	MATK
Entrez Gene	4145
Alt Symbol	CHK, CTK, HHYLTK, HYL, HYLTK, Lsk
Species	Human
Gene Type	protein-coding
Description	megakaryocyte-associated tyrosine kinase
Other Description	CSK homologous kinase|Csk-homologous kinase|Csk-type protein tyrosine kinase|HYL tyrosine kinase|hematopoietic consensus tyrosine-lacking kinase|hydroxyaryl-protein kinase|leukocyte carboxyl-terminal src kinase related|megakaryocyte-associated tyrosine-protein kinase|protein kinase HYL|tyrosine kinase MATK|tyrosine-protein kinase CTK|tyrosylprotein kinase
Swissprots	Q9NST8 B3KNZ9 P42679
Accessions	AAC60645 AAC62843 EAW69284 EAW69285 EAW69286 EAW69287 P42679 AB593100 BAJ84040 AK055395 BAG51511 AK225834 AK315646 BAG38013 AL137754 CAB70906 BC000114 AAH00114 BC003109 AAH03109 BG396388 BM925586 BQ109562 DA592994 L18974 AAA16703 S71669 AAB30995 X77278 CAA54493 XM_011528018 XP_011526320 XM_011528019 XP_011526321 NM_002378 NP_002369 NM_139354 NP_647611 NM_139355 NP_647612
Function	Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. {ECO:0000269|PubMed:9171348}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9171348}. Membrane {ECO:0000269|PubMed:9171348}. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
Tissue Specificity	Expressed in various myeloid cell lines, detected in brain and lung.
Top Pathways	Neurotrophin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Phosphotyrosine MATK / Megakaryocyte-associated Tyrosine-protein Kinase ELISA Kit - RAB0977 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Choline kinase alpha (CHKA), Human, ELISA Kit - CSB-EL005353HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.63 pg/ml-1000 pg/ml

Hydroxylysine, Hyl, General, ELISA Kit - E0742Ge from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 0.156-10 ng/mL

Human Hyl ELISA Kit - HH0323 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine Hyl ELISA Kit - AH0323 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

megakaryocyte-associated tyrosine kinase, ELISA Kit - MBS9321289 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Custom Human Phosphotyrosine MATK ELISA - PEL-MATK-Y-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human Hyl ELISA Kit - E019137 from Biobool Category ELISA Kit Sensitivity 1.0 ng/mL.

Human MATK ELISA Kit - E023953 from Biobool Category ELISA Kit

Human Hyl ELISA Kit - EHH0323 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

General Hydroxylysine ELISA Kit - EK2196 from Signalway Antibody Category ELISA Kit Prices $659.00 Sizes 1x96t Range 0.156-10 ng/mL

Human Hyl ELISA Kit - E019136 from Biobool Category ELISA Kit Sensitivity 0.056ng/ml

Human Megakaryocyte-associated tyrosine-protein kinase (MATK) ELISA Kit - AE34188HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t

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