MATK

Gene Symbol	MATK
Entrez Gene	4145
Alt Symbol	CHK, CTK, HHYLTK, HYL, HYLTK, Lsk
Species	Human
Gene Type	protein-coding
Description	megakaryocyte-associated tyrosine kinase
Other Description	CSK homologous kinase|Csk-homologous kinase|Csk-type protein tyrosine kinase|HYL tyrosine kinase|hematopoietic consensus tyrosine-lacking kinase|hydroxyaryl-protein kinase|leukocyte carboxyl-terminal src kinase related|megakaryocyte-associated tyrosine-protein kinase|protein kinase HYL|tyrosine kinase MATK|tyrosine-protein kinase CTK|tyrosylprotein kinase
Swissprots	Q9NST8 B3KNZ9 P42679
Accessions	AAC60645 AAC62843 EAW69284 EAW69285 EAW69286 EAW69287 P42679 AB593100 BAJ84040 AK055395 BAG51511 AK225834 AK315646 BAG38013 AL137754 CAB70906 BC000114 AAH00114 BC003109 AAH03109 BG396388 BM925586 BQ109562 DA592994 L18974 AAA16703 S71669 AAB30995 X77278 CAA54493 XM_011528018 XP_011526320 XM_011528019 XP_011526321 NM_002378 NP_002369 NM_139354 NP_647611 NM_139355 NP_647612
Function	Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. {ECO:0000269|PubMed:9171348}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9171348}. Membrane {ECO:0000269|PubMed:9171348}. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
Tissue Specificity	Expressed in various myeloid cell lines, detected in brain and lung.
Top Pathways	Neurotrophin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MATK protein fragment - ab158862 from Abcam Category Protein Source Wheat germ Species Human

Human MATK protein fragment - ab158863 from Abcam Category Protein Source Wheat germ Species Human

MATK Antibody Blocking Peptide - LS-E3131 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MATK Antibody Blocking Peptide - LS-E9217 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MATK Protein - H00004145-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MATK Protein - H00004145-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MATK Peptide - P2757 from Novus Biologicals Category Peptide Species Human

MATK-Antibody-N-term-Blocking-Peptide - BP7714a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Chk1 (active) recombinant protein - GTX65049 from GeneTex Category Protein Prices $329.00 Sizes 5 μg Source Baculovirus (Sf9 insect cells) Species Human

MATK - H00004145-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MATK - H00004145-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MATK - H00004145-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

MATK - H00004145-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MATK - H00004145-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MATK fusion protein - ag0128 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Lsk (V157) Peptide - BS9181P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Megakaryocyte-associated tyrosine-protein kinase(MATK) - CSB-YP013519HU CSB-EP013519HU CSB-BP013519HU CSB-MP013519HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Active human MATK full length protein - ab204136 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

MATK (transcript variant 3) - TP300454 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MATK (transcript variant 1) - TP323161 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human MATK GST - CSI13436 from Cell Science Prices $615.00 Sizes 10 μg Species Human

Recombinant Megakaryocyte Associated Tyrosine Kinase (MATK) - RPC638Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

MATK Recombinant Protein Antigen - NBP1-84487PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MATK-Antibody-Center-Blocking-Peptide - BP7714c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MATK Peptide, Human - M34GP09256H from Creative Peptides Category Peptide Source Synthetic. Species Human

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