BRD4

Gene Symbol	BRD4
Entrez Gene	23476
Alt Symbol	CAP, HUNK1, HUNKI, MCAP
Species	Human
Gene Type	protein-coding
Description	bromodomain containing 4
Other Description	bromodomain-containing 4|bromodomain-containing protein 4|chromosome-associated protein
Swissprots	Q4G0X8 O60885 O60433 Q96PD3
Accessions	AAC27978 EAW84469 EAW84470 EAW84471 EAW84472 EAW84473 O60885 AF252390 AF386649 AAL26987 AK307664 BC000156 AAH00156 BC008354 AAH08354 BC030158 AAH30158 BC035266 AAH35266 BC038988 AAH38988 BC047888 AAH47888 BC067129 AAH67129 BC091649 AAH91649 DQ580084 KF974357 AHK61044 Y12059 CAA72780 XM_011527854 XP_011526156 XM_011527855 XP_011526157 XM_011527856 XP_011526158 NM_014299 NP_055114 NM_058243 NP_490597
Function	Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure. During interphase, plays a key role in regulating the transcription of signal-inducible genes by associating with the P- TEFb complex and recruiting it to promoters: BRD4 is required to form the transcriptionally active P-TEFb complex by displacing negative regulators such as HEXIM1 and 7SKsnRNA complex from P- TEFb, thereby transforming it into an active form that can then phosphorylate the C-terminal domain (CTD) of RNA polymerase II. Promotes phosphorylation of 'Ser-2' of the C-terminal domain (CTD) of RNA polymerase II. According to a report, directly acts as an atypical
Subcellular Location	Nucleus. Chromosome. Note=Associates with acetylated chromatin. Released from chromatin upon deacetylation of histones that can be triggered by different signals such as activation of the JNK pathway or nocodazole treatment.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:12543779}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-BRD4 Antibody, Affinity Purified - PLA0227 from Sigma-Aldrich Prices $649.00 Sizes 100 µl

Bromodomain-containing protein 4 (BRD4), Human, ELISA Kit - E01B0836 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1mg/ml Range 1.0-25mg/ml

bromodomain containing 4, ELISA Kit - MBS945281 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human BRD4 is typically less than 4.68 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 18.75 pg/ml -1200 pg/ml.

Bromodomain containing protein 4 (BRD4), ELISA Kit - MBS7203252 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7243792 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7223313 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7250244 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7218501 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7252305 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7242877 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7231631 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7208647 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7207126 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7221215 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bromodomain-containing protein 4 (BRD4), ELISA Kit - MBS7208429 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Bromodomain-containing protein 4(BRD4) ELISA kit - CSB-EL002802HU from Cusabio Category ELISA Kit Sensitivity 4.68pg/ml Range 18.75 pg/ml-1200 pg/ml

Human BRD4 ELISA Kit - E005340 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human BRD4 is typically less than 4.68 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mea

BRD4 ELISA Kit (Human) (OKCA00624) - OKCA00624 from Aviva Systems Biology Category ELISA Kit Prices $590.00 Sizes 96 wells Sensitivity 4.68 pg/mL Range 18.75 pg/mL-1,200 pg/mL

anti-BRD4 antibody - ARG56161 from Arigo Biolaboratories Category ELISA Kit

Bromodomain Containing Protein 4 (BRD4) , ELISA Kit - MBS2088181 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.059ng/mL Range 0.156-10ng/mL

Human BRD4 ELISA Kit (Sandwich ELISA) - LS-F39048 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.059 Range 0.156-10 ng/ml

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