CNR2

Gene Symbol	CNR2
Entrez Gene	1269
Alt Symbol	CB-2, CB2, CX5
Species	Human
Gene Type	protein-coding
Description	cannabinoid receptor 2 (macrophage)
Other Description	cannabinoid receptor 2|testis-dominant CNR2 isoform CB2
Swissprots	P34972 C6ES44 Q6NSY0 Q5JRH7 Q6B0G7 Q4VBK8
Accessions	AAO92299 CAD22549 CAO02243 CAS97371 CAV28600 CAZ76867 EAW95099 EAW95100 P34972 AJ430063 CAD22548 AM156854 CAJ42137 AM156855 CAJ42138 AM156856 CAJ42139 BC069722 AAH69722 BC074767 AAH74767 BC095545 AAH95545 EU517121 ACD31539 FJ357036 X74328 CAA52376 XM_005245736 XP_005245793 XM_011540627 XP_011538929 XM_011540628 XP_011538930 XM_011540629 XP_011538931 NM_001841 NP_001832
Function	Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. {ECO:0000269|PubMed:10051546, ECO:0000269|PubMed:12663043, ECO:0000269|PubMed:12711605, ECO:0000269|PubMed:18692962}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell projection, dendrite {ECO:0000250}. Perikaryon {ECO:0000250}. Note=Localizes to apical dendrite of pyramidal neurons. {ECO:0000250}.
Tissue Specificity	Preferentially expressed in cells of the immune system with higher expression in B-cells and NK cells (at protein level). Expressed in skin in suprabasal layers and hair follicles (at protein level). Highly expressed in tonsil and to a lower extent in spleen, peripheral blood mononuclear cells, and thymus. PubMed:14657172 could not detect expression in normal brain. Expressed in brain by perivascular microglial cells and dorsal root ganglion sensory neurons (at protein level). Two isoforms are produced by alternative promoter usage and differ only in the 5' UTR: isoform CB2A is observed predominantly in testis with some expression in brain, while isoform CB2B is predominant in spleen and leukocytes. {ECO:0000269|PubMed:12153574, ECO:0000269|PubMed:12511587, ECO:0000269|PubMed:14657172, ECO:0000269|PubMed:15266552, ECO:0000269|PubMed:18692962, ECO:0000269|PubMed:19496827, ECO:0000269|PubMed:7556170}.
Top Pathways	Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat CNR2 / CB2 ELISA Kit (Sandwich ELISA) - LS-F7205 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 0.156-10 ng/ml

Cannabinoid receptor 2 (CNR2), Human, ELISA Kit - CSB-EL005679HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Cannabinoid receptor 2 (CNR2), Human, ELISA Kit - E01C1866 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7212043 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7211806 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7207466 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7232044 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7244347 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7200337 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7226770 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7200155 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7200948 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7223246 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7204819 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid receptor 2 (CNR2), ELISA Kit - MBS7210229 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cannabinoid receptor 2 (macrophage) , ELISA Kit - MBS914678 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cannabinoid Receptor 2, Macrophage (CNR2), ELISA Kit - MBS2019955 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.059ng/mL. Range 0.156-10ng/mL

ELISA Kit for Cannabinoid Receptor 2, Macrophage (CNR2) - SEE045Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Cannabinoid receptor 2(CNR2) ELISA kit - CSB-EL005679HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml Range 25 pg/ml - 1600 pg/ml

Human Cannabinoid receptor 2(CNR2) ELISA Kit - EKC32975 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,287.50 Sizes 96 t, 5x96t, 10x96t Sensitivity Request Information Range Request Information

Human CNR2 ELISA Kit - E006370 from Biobool Category ELISA Kit

anti-Cannabinoid Receptor 2 antibody - ARG63886 from Arigo Biolaboratories Category ELISA Kit

Cannabinoid Receptor 2, ELISA Kit - MBS763400 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/ml Range 62.5-4000pg/ml

Cannabinoid Receptor 2, ELISA Kit - MBS2533483 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

Mouse CNR2 / CB2 ELISA Kit (Sandwich ELISA) - LS-F32772 from LifeSpan Bioscience Category ELISA Kit Sensitivity 37.5 Range 0.156-10 ng/ml

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