GRHL3

Gene Symbol	GRHL3
Entrez Gene	57822
Alt Symbol	SOM, TFCP2L4, VWS2
Species	Human
Gene Type	protein-coding
Description	grainyhead-like 3 (Drosophila)
Other Description	grainyhead-like protein 3 homolog|sister of mammalian grainyhead|sister-of-mammalian grainyhead|transcription factor CP2-like 4|transcription factor hSOM1
Swissprots	G3XAF0 Q5TH78 Q8N407 B2RCL1 Q8TE85 A2A297 Q86Y06
Accessions	EAW95120 EAW95121 EAW95122 EAW95123 Q8TE85 AK074386 BAB85067 AK315164 BAG37608 AL137763 CAB70911 AY231160 AAO67370 AY231161 BC036890 AAH36890 BU848928 DA714132 EU446877 ABZ92406 XM_011541869 XP_011540171 XM_011541870 XP_011540172 NM_001195010 NP_001181939 NM_021180 NP_067003 NM_198173 NP_937816 NM_198174 NP_937817
Function	Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin (By similarity). Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' acting as an activator and repressor on distinct target genes (PubMed:21081122, PubMed:25347468). xhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair (By similarity). Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair but is essential to form the epidermal barrier with TGM3 as critical direct target gene among others. Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation after injury. Plays unique and cooperative roles with GRHL2 in establis
Subcellular Location	Nucleus {ECO:0000269|PubMed:21081122}.
Tissue Specificity	Expressed in brain, colon, pancreas, placenta and kidney. Isoform 1 is expressed in lung and tonsil. Isoform 2 is prostate-specific. {ECO:0000269|PubMed:12549979}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GRHL3 (C-12) - sc-398838 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

GRHL3 (G-15) - sc-131537 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GRHL3 (I-12) - sc-131538 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GRHL3 (S-19) - sc-101968 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Rabbit Clonality Polyclonal

Anti-GRHL3 antibody - ab50755 from Abcam Prices $370.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-GRHL3 antibody - ab129562 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 antibody - ab57612 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-GRHL3 antibody - ab93036 from Abcam Prices $370.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-GRHL3 antibody - ab93038 from Abcam Prices $370.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa1-30, AP) - LS-C214935 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa1-30, APC) - LS-C214936 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa1-30, Biotin) - LS-C214937 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa1-30, FITC) - LS-C214938 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa1-30, Azide-free, HRP) - LS-C214939 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa1-30, PE) - LS-C214940 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa428-477) - LS-C30200 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa101-201) - LS-C308116 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-GRHL3 Antibody (aa1-30) - LS-C321782 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa529-578) - LS-C31710 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa1-30) - LS-C166667 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-GRHL3 Antibody (aa431-480) IHC-plus™ - LS-B6813 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

GRHL3 Antibody - NBP1-80356 from Novus Biologicals Prices $299.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GRHL3 Antibody - NBP1-80355 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GRHL3 Antibody - NBP1-80018 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

GRHL3 Antibody - NBP2-16746 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Search more