PHOX2B

Gene Symbol PHOX2B
Entrez Gene 8929
Alt Symbol NBLST2, NBPhox, PMX2B
Species Human
Gene Type protein-coding
Description paired-like homeobox 2b
Other Description PHOX2B homeodomain protein|neuroblastoma Phox|neuroblastoma paired-type homeobox protein|paired mesoderm homeobox 2b|paired mesoderm homeobox protein 2B
Swissprots Q99453 Q6PJD9
Accessions AAD26698 BAA82670 EAW92989 Q99453 AI266171 BC017199 AAH17199 D82344 BAA11555 NM_003924 NP_003915
Function Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Tissue Specificity Expressed in neuroblastoma, brain and adrenal gland.

Phox2b (B-11) - sc-376997 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Phox2b (B-11): sc-376997. Western blot analysis of Phox2b expression in SK-N-SH (A), IMR-32 (B) and Neuro-2a (C) whole cell lysates.

Phox2b (C-20) - sc-13226 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Phox2b (C-20): sc-13226. Western blot analysis of Phox2b expression in human stomach tissue extract.

Phox2b (C-3) - sc-376993 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Phox2b (C-3): sc-376993. Western blot analysis of Phox2b expression in SK-N-SH (A) and IMR-32 (B) whole cell lysates.

Phox2b (H-20) - sc-13224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Phox2b (H-60) - sc-134605 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Phox2b (N-14) - sc-48627 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Phox2b (N-14): sc-48627. Western blot analysis of Phox2b expression in SK-N-SH whole cell lysate.

Anti-PHOX2B antibody - ab125046 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-PHOX2B antibody (ab125046) at 1 µg/mlLane 2 : Anti-PHOX2B antibody (ab125046) at 2 µg/mlLane 1 : 293 cell lysateLane 2 : 293 cell lysateLysates/proteins at 15 µg per lane.

Anti-PHOX2B antibody - ab170835 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PHOX2B antibody (ab170835) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

Anti-PHOX2B antibody [EPR14423] - C-terminal - ab183741 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14423
All lanes : Anti-PHOX2B antibody [EPR14423] - C-terminal (ab183741) at 1/1000 dilutionLane 1 : Neuro-2a cell lysateLane 2 : SH-SY5Y cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-PHOX2B Antibody (aa62-77) - LS-C17279 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa179-192) - LS-C112736 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PHOX2B Antibody - LS-C153203 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa1-94) - LS-C189830 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PHOX2B Antibody (aa104-130, AP) - LS-C266200 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa104-130, APC) - LS-C266201 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa104-130, Biotin) - LS-C266202 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa104-130, FITC) - LS-C266203 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa104-130, PE) - LS-C266206 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa104-130, Azide-free, HRP) - LS-C266204 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (Internal) - LS-C153759 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of PHOX2B in 293 cell lysate with PHOX2B antibody at (A) 1 and (B) 2 ug/ml.

Anti-PHOX2B Antibody (aa111-138) - LS-C323999 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (C-Terminus) - LS-C345694 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of PHX2B Antibody with human 721_B Whole Cell lysate.

Anti-PHOX2B Antibody (N-Terminus) - LS-C169534 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PHOX2B Antibody (aa104-130) - LS-C163688 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent image of U251 cell stained with PHOX2B Antibody. U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with PHOX2B primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). PHOX2B immunoreactivity is localized to Nucleus significantly.

PHOX2B Antibody [Unconjugated] - AF4940 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
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