PHOX2B

Gene Symbol PHOX2B
Entrez Gene 8929
Alt Symbol NBLST2, NBPhox, PMX2B
Species Human
Gene Type protein-coding
Description paired-like homeobox 2b
Other Description PHOX2B homeodomain protein|neuroblastoma Phox|neuroblastoma paired-type homeobox protein|paired mesoderm homeobox 2b|paired mesoderm homeobox protein 2B
Swissprots Q99453 Q6PJD9
Accessions AAD26698 BAA82670 EAW92989 Q99453 AI266171 BC017199 AAH17199 D82344 BAA11555 NM_003924 NP_003915
Function Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
Tissue Specificity Expressed in neuroblastoma, brain and adrenal gland.

Phox2b CRISPR/Cas9 KO Plasmid (h) - sc-401351 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b HDR Plasmid (h) - sc-401351-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b Double Nickase Plasmid (h) - sc-401351-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b Double Nickase Plasmid (h2) - sc-401351-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b CRISPR Activation Plasmid (h) - sc-401351-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b CRISPR Activation Plasmid (h2) - sc-401351-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b Lentiviral Activation Particles (h) - sc-401351-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b Lentiviral Activation Particles (h2) - sc-401351-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Phox2b siRNA (h) - sc-38764 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Phox2b shRNA Plasmid (h) - sc-38764-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Phox2b shRNA (h) Lentiviral Particles - sc-38764-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHOX2B RNAi - H00008929-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16755 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16755 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10442 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10442

PHOX2B siRNA (Human) - CRH5904 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PHOX2B (NM_003924.3) - SHH375052 from Creative biogene

Category siRNA
Species Reactivities Human

PHOX2B shRNA Plasmid (Human) - CHH5904 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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