| Gene Symbol | PHOX2B |
|---|---|
| Entrez Gene | 8929 |
| Alt Symbol | NBLST2, NBPhox, PMX2B |
| Species | Human |
| Gene Type | protein-coding |
| Description | paired-like homeobox 2b |
| Other Description | PHOX2B homeodomain protein|neuroblastoma Phox|neuroblastoma paired-type homeobox protein|paired mesoderm homeobox 2b|paired mesoderm homeobox protein 2B |
| Swissprots | Q99453 Q6PJD9 |
| Accessions | AAD26698 BAA82670 EAW92989 Q99453 AI266171 BC017199 AAH17199 D82344 BAA11555 NM_003924 NP_003915 |
| Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element. |
| Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
| Tissue Specificity | Expressed in neuroblastoma, brain and adrenal gland. |
paired-like homeobox 2b, ELISA Kit - MBS9339904 from MyBioSource
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Human PHOX2B ELISA Kit - E028137 from Biobool
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