Gene Symbol | PHOX2B |
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Entrez Gene | 8929 |
Alt Symbol | NBLST2, NBPhox, PMX2B |
Species | Human |
Gene Type | protein-coding |
Description | paired-like homeobox 2b |
Other Description | PHOX2B homeodomain protein|neuroblastoma Phox|neuroblastoma paired-type homeobox protein|paired mesoderm homeobox 2b|paired mesoderm homeobox protein 2B |
Swissprots | Q99453 Q6PJD9 |
Accessions | AAD26698 BAA82670 EAW92989 Q99453 AI266171 BC017199 AAH17199 D82344 BAA11555 NM_003924 NP_003915 |
Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
Tissue Specificity | Expressed in neuroblastoma, brain and adrenal gland. |
PHOX2B Antibody Blocking Peptide - LS-E934 from LifeSpan Bioscience
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PHOX2B Antibody Blocking Peptide - LS-E31289 from LifeSpan Bioscience
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PHOX2B Antibody Blocking Peptide - LS-E13799 from LifeSpan Bioscience
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PHOX2B Antibody Blocking Peptide - LS-E26914 from LifeSpan Bioscience
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PHOX2B-Antibody-Center-Blocking-peptide - BP11341c from Abgent, a WuXi AppTec company
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PHOX2B blocking peptide - GTX88535-PEP from GeneTex
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PHOX2B Peptide - AC21-1746-P from Abcore
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PHOX2B (Center) Control Peptide - AP55672CP-N from Acris Antibodies
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PHOX2B Peptide - 6913P from ProSci
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PHOX2B Peptide - 46-976P from ProSci
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PHOX2B fusion protein - Ag13196 from Proteintech Group
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Recombinant Human PHOX2B - PHOX2B-668H from Creative Biomart
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Recombinant Human Paired mesoderm homeobox protein 2B(PHOX2B) - CSB-YP859099HU CSB-EP859099HU CSB-BP859099HU CSB-MP859099HU from Cusabio
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Paired mesoderm homeobox protein 2B (PHOX2B), Recombinant Protein - MBS1475052 from MyBioSource
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PHOX2B, Peptide - MBS426899 from MyBioSource
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PHOX2B Peptide, Human - M34GP11725H from Creative Peptides
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PHOX2B Recombinant Protein Antigen - NBP2-57536PEP from Novus Biologicals
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