CPLX1

Gene Symbol	CPLX1
Entrez Gene	10815
Alt Symbol	CPX-I, CPX1
Species	Human
Gene Type	protein-coding
Description	complexin 1
Other Description	CPX I|complexin I|complexin-1|synaphin 2|synaphin-2
Swissprots	A6NI80 B2R4R5 F1T0G1 O14810 D3DVN3
Accessions	EAW82647 EAW82648 EAW82649 O14810 AB593095 BAJ84035 AF022383 AAB72108 AK126578 AK311921 BAG34862 BC002471 AAH02471 BT007029 AAP35676 KJ534815 AHW56455 XM_011513391 XP_011511693 NM_006651 NP_006642
Function	Positively regulates a late step in synaptic vesicle exocytosis. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Note=Enriched at synaptic-releasing sites in mature neurons. {ECO:0000250}.
Tissue Specificity	Nervous system. In hippocampus and cerebellum, expressed mainly by inhibitory neurons. Overexpressed in substantia nigra from patients with Parkinson disease. {ECO:0000269|PubMed:11483314, ECO:0000269|PubMed:15526345, ECO:0000269|PubMed:9853440}.
Top Pathways	Synaptic vesicle cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Complexin-1 (CPLX1), Human, ELISA Kit - E01C2002 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Probable carboxypeptidase X1 (CPXM1), Human, ELISA Kit - CSB-EL005929HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Carboxypeptidase X1 (CPX1), ELISA Kit - MBS9312074 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 1 (CPLX1), ELISA Kit - MBS7228794 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7224068 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7238955 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7209537 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7228518 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7206267 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7250344 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7223998 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7203809 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7236332 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-1 (CPLX1), ELISA Kit - MBS7238141 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human CPX1 ELISA Kit - E006618 from Biobool Category ELISA Kit

Human CPLX1 ELISA Kit - E079927 from Biobool Category ELISA Kit

anti-Complexin-1 antibody - ARG55218 from Arigo Biolaboratories Category ELISA Kit

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