TFAM

Gene Symbol	TFAM
Entrez Gene	7019
Alt Symbol	MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3
Species	Human
Gene Type	protein-coding
Description	transcription factor A, mitochondrial
Other Description	mitochondrial transcription factor 1|mitochondrial transcription factor A|transcription factor 6|transcription factor 6-like 1|transcription factor 6-like 2 (mitochondrial transcription factor)|transcription factor 6-like 3
Swissprots	A9QXC6 Q5U0C6 Q00059 B5BU05 A8MRB2
Accessions	ADP91974 ADP91975 ADP91976 ADP91977 ADP91978 ADP91979 ADP91980 ADP91981 ADP91982 ADP91983 ADP91984 ADP91985 ADP91986 ADP91987 ADP91988 ADP91989 ADP91990 ADP91991 ADP91992 ADP91993 ADP91994 ADP91995 ADP91996 ADP91997 ADP91998 ADP91999 ADP92000 ADP92001 ADP92002 ADP92003 ADP92004 ADP92005 ADP92006 ADP92007 ADP92008 ADP92009 ADP92010 ADP92011 ADP92012 ADP92013 CAA45562 EAW54171 EAW54172 EAW54173 EAW54174 EAW54175 Q00059 AB451241 BAG70055 AB451366 BAG70180 AK312558 BAG35455 BC018628 AAH18628 BC029815 BC104482 AAI04483 BC126366 AAI26367 BM455062 BT019658 AAV38464 BT019659 AAV38465 CN478914 CR407653 CAG28581 CR736151 DB456976 EU279428 ABX72056 HQ258758 ADR83509 M62810 AAA59849 XM_011540120 XP_011538422 XM_011540121 XP_011538423 NM_001270782 NP_001257711 NM_003201 NP_003192 NR_073073 NM_012251
Function	Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. {ECO:0000269|PubMed:1737790, ECO:0000269|PubMed:19304746, ECO:0000269|PubMed:20410300, ECO:0000269|PubMed:22037171, ECO:0000269|PubMed:22037172, ECO:0000269|PubMed:22841477}.
Subcellular Location	Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Top Pathways	Huntington's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TFAM-cDNA-Clone - DC14419 from Abgent, a WuXi AppTec company Prices $332.10 Sizes 10 µg Species Human Accession BC126366

TFAM - MBS1276975 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC126366

Human TFAM ORF Clone(NM_003201.2) - CDCL178271 from Creative Biomart Species Human Accession NM_003201.2

human TFAM ORF clone - CDCH090396 from Creative Biomart Species Human Accession NM_003201

human TFAM ORF clone - CDCH090397 from Creative Biomart Species Human Accession NM_003201

Human TFAM Gene ORF cDNA clone in cloning vector - HG15937-G from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15937-ACR from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15937-ANR from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15937-ACG from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15937-ANG from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, N-HA tag - HG15937-NY from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15937-NF from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, N-His tag - HG15937-NH from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, C-His tag - HG15937-CH from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15937-CF from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid - HG15937-UT from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15937-CM from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15937-NM from Sino Biological Species Human

Human TFAM Gene ORF cDNA clone expression plasmid, C-HA tag - HG15937-CY from Sino Biological Species Human

Human TFAM ORF Clone (BC126366) - CDCS411193 from Creative biogene Species Human Accession Q00059

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