TFAM

Gene Symbol TFAM
Entrez Gene 7019
Alt Symbol MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3
Species Human
Gene Type protein-coding
Description transcription factor A, mitochondrial
Other Description mitochondrial transcription factor 1|mitochondrial transcription factor A|transcription factor 6|transcription factor 6-like 1|transcription factor 6-like 2 (mitochondrial transcription factor)|transcription factor 6-like 3
Swissprots A9QXC6 Q5U0C6 Q00059 B5BU05 A8MRB2
Accessions ADP91974 ADP91975 ADP91976 ADP91977 ADP91978 ADP91979 ADP91980 ADP91981 ADP91982 ADP91983 ADP91984 ADP91985 ADP91986 ADP91987 ADP91988 ADP91989 ADP91990 ADP91991 ADP91992 ADP91993 ADP91994 ADP91995 ADP91996 ADP91997 ADP91998 ADP91999 ADP92000 ADP92001 ADP92002 ADP92003 ADP92004 ADP92005 ADP92006 ADP92007 ADP92008 ADP92009 ADP92010 ADP92011 ADP92012 ADP92013 CAA45562 EAW54171 EAW54172 EAW54173 EAW54174 EAW54175 Q00059 AB451241 BAG70055 AB451366 BAG70180 AK312558 BAG35455 BC018628 AAH18628 BC029815 BC104482 AAI04483 BC126366 AAI26367 BM455062 BT019658 AAV38464 BT019659 AAV38465 CN478914 CR407653 CAG28581 CR736151 DB456976 EU279428 ABX72056 HQ258758 ADR83509 M62810 AAA59849 XM_011540120 XP_011538422 XM_011540121 XP_011538423 NM_001270782 NP_001257711 NM_003201 NP_003192 NR_073073 NM_012251
Function Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. {ECO:0000269|PubMed:1737790, ECO:0000269|PubMed:19304746, ECO:0000269|PubMed:20410300, ECO:0000269|PubMed:22037171, ECO:0000269|PubMed:22037172, ECO:0000269|PubMed:22841477}.
Subcellular Location Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Top Pathways Huntington's disease

mtTFA CRISPR/Cas9 KO Plasmid (h) - sc-401208 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA HDR Plasmid (h) - sc-401208-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA Double Nickase Plasmid (h) - sc-401208-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA Double Nickase Plasmid (h2) - sc-401208-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA CRISPR Activation Plasmid (h) - sc-401208-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA CRISPR Activation Plasmid (h2) - sc-401208-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA Lentiviral Activation Particles (h) - sc-401208-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA Lentiviral Activation Particles (h2) - sc-401208-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mtTFA siRNA (h) - sc-38053 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mtTFA shRNA Plasmid (h) - sc-38053-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mtTFA shRNA (h) Lentiviral Particles - sc-38053-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mtTFA RNAi - H00007019-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU047401 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21242 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21242 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TFAM siRNA (Human) - CRH4794 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFAM - MBS8202764 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TFAM (NM_003201.2) - SHH426072 from Creative biogene

Category siRNA
Species Reactivities Human

Human TFAM siRNA - orb265296 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFAM shRNA Plasmid (Human) - CHH4794 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TFAM miRNA 3'UTR clone - MiUTR3H-03374 from Creative biogene

Species Reactivities Human
Search more