TFAM

Gene Symbol	TFAM
Entrez Gene	7019
Alt Symbol	MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3
Species	Human
Gene Type	protein-coding
Description	transcription factor A, mitochondrial
Other Description	mitochondrial transcription factor 1|mitochondrial transcription factor A|transcription factor 6|transcription factor 6-like 1|transcription factor 6-like 2 (mitochondrial transcription factor)|transcription factor 6-like 3
Swissprots	A9QXC6 Q5U0C6 Q00059 B5BU05 A8MRB2
Accessions	ADP91974 ADP91975 ADP91976 ADP91977 ADP91978 ADP91979 ADP91980 ADP91981 ADP91982 ADP91983 ADP91984 ADP91985 ADP91986 ADP91987 ADP91988 ADP91989 ADP91990 ADP91991 ADP91992 ADP91993 ADP91994 ADP91995 ADP91996 ADP91997 ADP91998 ADP91999 ADP92000 ADP92001 ADP92002 ADP92003 ADP92004 ADP92005 ADP92006 ADP92007 ADP92008 ADP92009 ADP92010 ADP92011 ADP92012 ADP92013 CAA45562 EAW54171 EAW54172 EAW54173 EAW54174 EAW54175 Q00059 AB451241 BAG70055 AB451366 BAG70180 AK312558 BAG35455 BC018628 AAH18628 BC029815 BC104482 AAI04483 BC126366 AAI26367 BM455062 BT019658 AAV38464 BT019659 AAV38465 CN478914 CR407653 CAG28581 CR736151 DB456976 EU279428 ABX72056 HQ258758 ADR83509 M62810 AAA59849 XM_011540120 XP_011538422 XM_011540121 XP_011538423 NM_001270782 NP_001257711 NM_003201 NP_003192 NR_073073 NM_012251
Function	Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. {ECO:0000269|PubMed:1737790, ECO:0000269|PubMed:19304746, ECO:0000269|PubMed:20410300, ECO:0000269|PubMed:22037171, ECO:0000269|PubMed:22037172, ECO:0000269|PubMed:22841477}.
Subcellular Location	Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Top Pathways	Huntington's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human mtTFA full length protein - ab103784 from Abcam Category Protein Source E. coli Species Human

Human mtTFA peptide - ab47516 from Abcam Category Peptide

Mouse mtTFA peptide - ab171292 from Abcam Category Peptide

MtTFA / TFAM Antibody Blocking Peptide - LS-E144 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MtTFA / TFAM Antibody Blocking Peptide - LS-E10970 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MtTFA / TFAM Antibody Blocking Peptide - LS-E13267 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MtTFA / TFAM Antibody Blocking Peptide - LS-E21486 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MtTFA / TFAM Antibody Blocking Peptide - LS-E21487 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human mtTFA Protein - NBP1-50977 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 10 µg, 50 µg Source E. coli Species Human

mtTFA Recombinant Protein - P3421 from Novus Biologicals Category Protein Prices $549.00 Sizes 10 µg Species Human

TFAM-Antibody-C-term-Blocking-peptide - BP10271b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

mtTFA Protein - GTX112760-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Human TFAM protein - orb169413 from Biorbyt Category Protein Prices $230.00, $442.00, $1,811.00 Sizes 1 μg, 5 μg, 50 μg Source E. coli Species Human

TFAM Blocking Peptide - 33R-10974 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

TFAM Blocking Peptide - 33R-4981 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TFAM Blocking Peptide - 33R-4982 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TFAM protein (His tag) - 80R-1655 from Fitzgerald Category Protein Prices $255.00 Sizes 10 µg Source E.coli

Human TFAM Protein - abx069399 from Abbexa Category Protein Source E.coli Species Human

TFAM / TCF6 (43-246, His-tag) - AR09837PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

TFAM / TCF6 (43-246, His-tag) - AR09837PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

TFAM / TCF6 - P3421 from Acris Antibodies Category Protein Prices $500.00 Sizes 10 µg Species Human

TFAM, 43-246aa, Human, His tag, E.coli - 01-P0897 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

Transcription Factor A, Mitochondrial (TFAM), Human - 20-9222 from ARP American Research Products Category Protein Prices $525.00 Sizes 50 µg Source E.coli Species Human

TFAM fusion protein - Ag21196 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TFAM fusion protein - Ag18299 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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