TFAM

Gene Symbol	TFAM
Entrez Gene	7019
Alt Symbol	MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3
Species	Human
Gene Type	protein-coding
Description	transcription factor A, mitochondrial
Other Description	mitochondrial transcription factor 1|mitochondrial transcription factor A|transcription factor 6|transcription factor 6-like 1|transcription factor 6-like 2 (mitochondrial transcription factor)|transcription factor 6-like 3
Swissprots	A9QXC6 Q5U0C6 Q00059 B5BU05 A8MRB2
Accessions	ADP91974 ADP91975 ADP91976 ADP91977 ADP91978 ADP91979 ADP91980 ADP91981 ADP91982 ADP91983 ADP91984 ADP91985 ADP91986 ADP91987 ADP91988 ADP91989 ADP91990 ADP91991 ADP91992 ADP91993 ADP91994 ADP91995 ADP91996 ADP91997 ADP91998 ADP91999 ADP92000 ADP92001 ADP92002 ADP92003 ADP92004 ADP92005 ADP92006 ADP92007 ADP92008 ADP92009 ADP92010 ADP92011 ADP92012 ADP92013 CAA45562 EAW54171 EAW54172 EAW54173 EAW54174 EAW54175 Q00059 AB451241 BAG70055 AB451366 BAG70180 AK312558 BAG35455 BC018628 AAH18628 BC029815 BC104482 AAI04483 BC126366 AAI26367 BM455062 BT019658 AAV38464 BT019659 AAV38465 CN478914 CR407653 CAG28581 CR736151 DB456976 EU279428 ABX72056 HQ258758 ADR83509 M62810 AAA59849 XM_011540120 XP_011538422 XM_011540121 XP_011538423 NM_001270782 NP_001257711 NM_003201 NP_003192 NR_073073 NM_012251
Function	Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. {ECO:0000269|PubMed:1737790, ECO:0000269|PubMed:19304746, ECO:0000269|PubMed:20410300, ECO:0000269|PubMed:22037171, ECO:0000269|PubMed:22037172, ECO:0000269|PubMed:22841477}.
Subcellular Location	Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Top Pathways	Huntington's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

mtTFA (TFAM ) Human SimpleStep ELISA™ Kit - ab181425 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 536 pg/ml Range 0.94 ng/ml - 60 ng/ml

mtTFA (TFAM) Human ELISA Kit - ab123455 from Abcam Category ELISA Kit Sensitivity 0.05 ng/ml Range Sample specific recoverySample typeAverage %RangeCell Lysate10µg/ml - 200µg/ml

Human MtTFA / TFAM ELISA Kit (Sandwich ELISA) - LS-F7151 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.124 ng/ml Range 0.313-20 ng/ml

Mouse MtTFA / TFAM ELISA Kit (Sandwich ELISA) - LS-F9115 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.313-20 ng/ml

Transcription Factor A, Mitochondrial (TFAM), Human, ELISA Kit - SEH050Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.109ng/mL Range 0.312-20ng/mL

TFAM (Human) IP-WB Antibody Pair - H00007019-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Transcription Factor A, Mitochondrial, ELISA Kit - MBS079163 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor A, Mitochondrial, ELISA Kit - MBS077163 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0pg/ml. Range 6.25pg/ml-200pg/ml.

Transcription Factor A, Mitochondrial, ELISA Kit - MBS057469 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor A, Mitochondrial, ELISA Kit - MBS103882 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor A, Mitochondrial, ELISA Kit - MBS101840 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor A, Mitochondrial, ELISA Kit - MBS057331 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription Factor A, Mitochondrial (TFAM), ELISA Kit - MBS2020891 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.121ng/mL. Range 0.312-20ng/mL.

Transcription Factor A, Mitochondrial (TFAM), ELISA Kit - MBS2020535 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.107ng/mL. Range 0.313-20ng/mL

ELISA Kit for Transcription Factor A, Mitochondrial (TFAM) - SEH050Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Transcription Factor A, Mitochondrial (TFAM) - SEH050Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.107ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Transcription Factor A, Mitochondrial (TFAM) - SEH050Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Transcription Factor A, Mitochondrial, ELISA Kit - MBS100629 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Transcription Factor A, Mitochondrial (TFAM) ELISA Kit - EKU07778 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.124 ng/mL Range 0.312-20 ng/mL

Human TFAM ELISA Kit - abx153259 from Abbexa Category ELISA Kit Sensitivity 0.109 ng/ml Range 0.313 ng/ml - 20 ng/ml

Transcription Factor A, Mitochondrial (TFAM), Human, ELISA Kit - DL-TFAM-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human TFAM ELISA Kit - abx572500 from Abbexa Category ELISA Kit Sensitivity 0.109 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human TFAM ELISA Kit - E038791 from Biobool Category ELISA Kit Sensitivity Typically less than 0.124ng/mL.

TFAM ELISA Kit (Human) (OKCD01018) - OKCD01018 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.124 ng/mL Range 0.312-20 ng/mL

anti-TFAM antibody - ARG56265 from Arigo Biolaboratories Category ELISA Kit

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