Gene Symbol | NEURL2 |
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Entrez Gene | 140825 |
Alt Symbol | C20orf163, OZZ, OZZ-E3 |
Species | Human |
Gene Type | protein-coding |
Description | neuralized E3 ubiquitin protein ligase 2 |
Other Description | neuralized homolog 2|neuralized-like protein 2 |
Swissprots | Q3KR34 Q9BR09 |
Accessions | EAW75790 Q9BR09 AJ295985 CAC82498 AK054821 BAB70810 AW298115 AW515245 BC074737 AAH74737 BC105935 AAI05936 BC107485 AAI07486 HY058356 NM_001278535 NP_001265464 NM_080749 NP_542787 |
Function | Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed specifically in skeletal and cardiac muscles. {ECO:0000269|PubMed:14960280}. |
Human NEURL2 full length protein - ab171589 from Abcam
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NEURL2 Antibody Blocking Peptide - LS-E18897 from LifeSpan Bioscience
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NEURL2 Antibody Blocking Peptide - LS-E18896 from LifeSpan Bioscience
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Recombinant Human NEURL2 Protein - NBP2-23277 from Novus Biologicals
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Human NEURL2 protein - orb191334 from Biorbyt
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NEURL2 Blocking Peptide - 33R-9509 from Fitzgerald
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NEURL2 Blocking Peptide - 33R-5586 from Fitzgerald
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NEURL2 protein (His tag) - 80R-3003 from Fitzgerald
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NEURL2 Blocking Peptide - abx064064 from Abbexa
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NEURL2 (1-285, His-tag) - AR51121PU-N from Acris Antibodies
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NEURL2 (1-285, His-tag) - AR51121PU-S from Acris Antibodies
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NEURL2, 1-285aa, Human, His tag, E.coli - 01-P2297 from ARP American Research Products
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NEURL2 fusion protein - ag15670 from Proteintech Group
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NEURL2 fusion protein - Ag15874 from Proteintech Group
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Recombinant Human NEURL2, His-tagged - NEURL2-2297H from Creative Biomart
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NEURL2 Blocking Peptide - CBP2870 from Cohesion Biosciences
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Recombinant Human Neuralized-like protein 2(NEURL2) - CSB-YP861118HU CSB-EP861118HU CSB-BP861118HU CSB-MP861118HU from Cusabio
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NEuRL2, 1-285aa, Human, His tag, E.coli (Denatured) - ATGP2297 from ATGen
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Neuralized Homolog 2 Protein (Recombinant) - abx262692 from Abbexa
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NEURL2 - TP312983 from Acris Antibodies
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NEURL2 Protein - NBP2-13654PEP from Novus Biologicals
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NEURL2 Peptide, Human - M34GP10312H from Creative Peptides
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NEURL2 Antibody - SH-A13982 from Novatein Biosciences
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NEuRL2 - PAT-82296-1 from Nordic BioSite
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NEuRL2 - PAT-82296-2 from Nordic BioSite
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