DNASE2

Gene Symbol	DNASE2
Entrez Gene	1777
Alt Symbol	DNASE2A, DNL, DNL2
Species	Human
Gene Type	protein-coding
Description	deoxyribonuclease II, lysosomal
Other Description	DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase|deoxyribonuclease II alpha|deoxyribonuclease-2-alpha|lysosomal DNase II
Swissprots	O00115 O43910 B7Z4K6 B2RD06
Accessions	AAB51172 BAB20386 BAB55597 BAB55598 EAW84320 EAW84321 EAW84322 O00115 AB004574 BAA28623 AF045937 AAC35751 AF047016 AAC77366 AF060222 AAC39852 AK075449 BAG52141 AK297493 BAH12592 AK311145 AK315358 BAG37753 BC010419 AAH10419 BC065209 AAH65209 BT007047 AAP35696 BX394955 FJ752529 ACN63522 NM_001375 NP_001366
Function	Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Subcellular Location	Lysosome.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DNASE2 293T Cell Transient Overexpression Lysate(Denatured) - H00001777-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

DNASE2 293 Cell Lysate - 409357 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

DNase II Overexpression Lysate (Denatured) - H00001777-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

DNase II Overexpression Lysate (Native) - NBL1-09964 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

DNASE2 Over-expression Lysate Product - GWB-7F6AA8 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human DNASE2 Knockdown Stable Cell Line - CSC-DC004451 from Creative biogene Category Cell Line Species Human

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