DNASE2

Gene Symbol	DNASE2
Entrez Gene	1777
Alt Symbol	DNASE2A, DNL, DNL2
Species	Human
Gene Type	protein-coding
Description	deoxyribonuclease II, lysosomal
Other Description	DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase|deoxyribonuclease II alpha|deoxyribonuclease-2-alpha|lysosomal DNase II
Swissprots	O00115 O43910 B7Z4K6 B2RD06
Accessions	AAB51172 BAB20386 BAB55597 BAB55598 EAW84320 EAW84321 EAW84322 O00115 AB004574 BAA28623 AF045937 AAC35751 AF047016 AAC77366 AF060222 AAC39852 AK075449 BAG52141 AK297493 BAH12592 AK311145 AK315358 BAG37753 BC010419 AAH10419 BC065209 AAH65209 BT007047 AAP35696 BX394955 FJ752529 ACN63522 NM_001375 NP_001366
Function	Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Subcellular Location	Lysosome.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DNase II peptide - ab8373 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human DNase II full length protein - ab131771 from Abcam Category Protein Source Wheat germ Species Human

Human DNase II full length protein - ab131772 from Abcam Category Protein Source Wheat germ Species Human

Human DNase II protein fragment - ab158296 from Abcam Category Protein Source Wheat germ Species Human

DNASE2 / DNase II Antibody Blocking Peptide - LS-E29875 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human DNase II Protein - H00001777-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

DNase II Recombinant Protein - H00001777-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human DNase II Protein - H00001777-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DNase II Blocking Peptide - NBP1-76971PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Deoxyribonuclease-2-alpha - H00001777-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Deoxyribonuclease-2-alpha - H00001777-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Deoxyribonuclease-2-alpha - H00001777-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

Deoxyribonuclease-2-alpha - H00001777-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Deoxyribonuclease-2-alpha - H00001777-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Deoxyribonuclease-2-alpha - H00001777-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Deoxyribonuclease-2-alpha - H00001777-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Deoxyribonuclease-2-alpha - H00001777-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DNase II Peptide - 2059P from ProSci Category Peptide Species Human

DNASE2 fusion protein - ag8781 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DNASE2 fusion protein - Ag8952 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Deoxyribonuclease II (DNASEII) - RPC247Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Deoxyribonuclease II (DNASEII) - RPC247Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Deoxyribonuclease-2-alpha(DNASE2) - CSB-YP007053HU CSB-EP007053HU CSB-BP007053HU CSB-MP007053HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Deoxyribonuclease-2-alpha - TP309573 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DNase II Protein - NBP2-39068PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

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