DNASE2

Gene Symbol DNASE2
Entrez Gene 1777
Alt Symbol DNASE2A, DNL, DNL2
Species Human
Gene Type protein-coding
Description deoxyribonuclease II, lysosomal
Other Description DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase|deoxyribonuclease II alpha|deoxyribonuclease-2-alpha|lysosomal DNase II
Swissprots O00115 O43910 B7Z4K6 B2RD06
Accessions AAB51172 BAB20386 BAB55597 BAB55598 EAW84320 EAW84321 EAW84322 O00115 AB004574 BAA28623 AF045937 AAC35751 AF047016 AAC77366 AF060222 AAC39852 AK075449 BAG52141 AK297493 BAH12592 AK311145 AK315358 BAG37753 BC010419 AAH10419 BC065209 AAH65209 BT007047 AAP35696 BX394955 FJ752529 ACN63522 NM_001375 NP_001366
Function Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Subcellular Location Lysosome.
Top Pathways Lysosome

DNase II CRISPR/Cas9 KO Plasmid (h) - sc-405046 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II HDR Plasmid (h) - sc-405046-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II Double Nickase Plasmid (h) - sc-405046-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II Double Nickase Plasmid (h2) - sc-405046-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II CRISPR Activation Plasmid (h) - sc-405046-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II CRISPR Activation Plasmid (h2) - sc-405046-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II Lentiviral Activation Particles (h) - sc-405046-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II Lentiviral Activation Particles (h2) - sc-405046-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNase II siRNA (h) - sc-41507 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNase II shRNA Plasmid (h) - sc-41507-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNase II shRNA (h) Lentiviral Particles - sc-41507-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNase II RNAi - H00001777-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7392 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7392 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DNASE2 siRNA (Human) - CRH1235 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNASE2 - MBS8225109 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DNASE2 (NM_001375.2) - SHH279833 from Creative biogene

Category siRNA
Species Reactivities Human

Human DNASE2 siRNA - orb261737 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNASE2 shRNA Plasmid (Human) - CHH1235 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DNASE2 miRNA 3'UTR clone - MiUTR1H-02934 from Creative biogene

Species Reactivities Human
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