DNASE2

Gene Symbol	DNASE2
Entrez Gene	1777
Alt Symbol	DNASE2A, DNL, DNL2
Species	Human
Gene Type	protein-coding
Description	deoxyribonuclease II, lysosomal
Other Description	DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase|deoxyribonuclease II alpha|deoxyribonuclease-2-alpha|lysosomal DNase II
Swissprots	O00115 O43910 B7Z4K6 B2RD06
Accessions	AAB51172 BAB20386 BAB55597 BAB55598 EAW84320 EAW84321 EAW84322 O00115 AB004574 BAA28623 AF045937 AAC35751 AF047016 AAC77366 AF060222 AAC39852 AK075449 BAG52141 AK297493 BAH12592 AK311145 AK315358 BAG37753 BC010419 AAH10419 BC065209 AAH65209 BT007047 AAP35696 BX394955 FJ752529 ACN63522 NM_001375 NP_001366
Function	Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Subcellular Location	Lysosome.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DNASE2 cDNA clone(NM_001375.2) - CDFH005305 from Creative Biomart Species Human Accession NM_001375.2

Human DNASE2 cDNA clone(NM_001375.2) - CDFH005306 from Creative Biomart Species Human Accession NM_001375.2

Human DNASE2 ORF Clone(NM_001375.2) - CDCL161347 from Creative Biomart Species Human Accession NM_001375.2

Human DNASE2 ORF Clone(NM_001375.2) - CDCR280640 from Creative Biomart Species Human Accession NM_001375.2

Human DNASE2 ORF Clone(NM_001375.2) - CDCR280641 from Creative Biomart Species Human Accession NM_001375.2

Human DNASE2 ORF Clone(NM_001375.2) - CDCR280642 from Creative Biomart Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone) - HG16372-G from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG16372-UT from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged - HG16372-NF from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged - HG16372-CF from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 natural ORF mammalian expression plasmid, C-OFPSpark / RFP tag - HG16372-ACR from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG16372-NM from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG16372-CM from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG16372-CY from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG16372-NH from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-tagged - HG16372-ACG from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - HG16372-CH from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged - HG16372-NY from Sino Biological Species Human Accession NM_001375.2

Human DNASE2 ORF Clone(NM_001375.2) - CDCR280640 from Creative biogene Species Human

Human DNASE2 cDNA Clone(NM_001375.2) - CDFH005305 from Creative biogene Species Human

Human DNASE2 cDNA Clone(NM_001375.2) - CDFH005306 from Creative biogene Species Human

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