DNASE2

Gene Symbol DNASE2
Entrez Gene 1777
Alt Symbol DNASE2A, DNL, DNL2
Species Human
Gene Type protein-coding
Description deoxyribonuclease II, lysosomal
Other Description DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase|deoxyribonuclease II alpha|deoxyribonuclease-2-alpha|lysosomal DNase II
Swissprots O00115 O43910 B7Z4K6 B2RD06
Accessions AAB51172 BAB20386 BAB55597 BAB55598 EAW84320 EAW84321 EAW84322 O00115 AB004574 BAA28623 AF045937 AAC35751 AF047016 AAC77366 AF060222 AAC39852 AK075449 BAG52141 AK297493 BAH12592 AK311145 AK315358 BAG37753 BC010419 AAH10419 BC065209 AAH65209 BT007047 AAP35696 BX394955 FJ752529 ACN63522 NM_001375 NP_001366
Function Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Subcellular Location Lysosome.
Top Pathways Lysosome

DNase II (M-183) - sc-366065 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

DNase II (A-20) - sc-19272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DNase II (H-105) - sc-292979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

DNase II (N-13) - sc-19271 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DNase II (N-13): sc-19271. Western blot analysis of DNase II expression in mouse liver extract.

Anti-DNase II antibody - ab8119 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DNase II antibody (ab8119) at 1/500 dilutionLane 1 : Human spleen tissue lysate with absence of blocking peptideLane 2 : Human spleen tissue lysate with presence of blocking peptide

Anti-DNase II antibody - ab168782 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-DNase II antibody (ab168782) at 1 µg/mlLane 1 : DNase II transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-DNase II antibody - ab115233 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human thymus tissue (formalin-fixed, paraffin-embedded) stained with ab115233 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.

Anti-DNASE2 / DNase II Antibody (C-Terminus) - LS-C22785 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-DNASE2 / DNase II Antibody (C-Terminus) - LS-C22784 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DNASE2 / DNase II Antibody - LS-C26602 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of anti-DNase II (CT) antibody at 1 ug/ml on human spleen tissue lysate in the absence (1) and presence (2) of blocking peptide.

Anti-DNASE2 / DNase II Antibody (C-Terminus) - LS-C121722 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DNASE2 / DNase II Antibody (aa347-360) - LS-C125455 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DNASE2 / DNase II Antibody - LS-C307292 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-DNASE2 / DNase II Antibody - LS-C310167 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DNASE2 / DNase II Antibody - LS-C310168 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DNASE2 / DNase II Antibody (C-Terminus) - LS-C187749 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of human spleen with Rabbit anti-DNASE-II

Anti-DNASE2 / DNase II Antibody (aa347-360) IHC-plus™ - LS-B560 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DNASE2 / DNase II antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B560 concentration 5 ug/ml.

DNase II Antibody - NBP1-76971 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DNase II Antibody [NBP1-76971] - Human spleen tissue lysate in the absence (lane 1) or presence (lane 2) of blocking peptide with DNase antibody II at 1:500 dilution.

DNase II Antibody - H00001777-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DNase II Antibody [H00001777-B01P] - Analysis of DNASE2 expression in transfected 293T cell line by DNASE2 polyclonal antibody. Lane 1: DNASE2 transfected lysate(39.6 KDa). Lane 2: Non-transfected lysate.

DNase II Antibody - NBP2-39068 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: DNase II Antibody [NBP2-39068] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.

DNase II Antibody - NB100-94212 from Novus Biologicals

Prices $449.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DNase II Antibody [NB100-94212] - Western blot analysis of DNase II in human spleen tissue lysate in the absence (lane 1) or presence (lane 2) of blocking peptide with anti-DNase II (CT) at 1:500 dilution.

DNase II Antibody - H00001777-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DNase II Antibody [H00001777-A01] - DNASE2 polyclonal antibody (A01), Lot # 051024JC01 Western Blot analysis of DNASE2 expression in MES-SA/Dx5 ( Cat # L021V1 ).

DNase II Antibody - H00001777-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DNase II Antibody [H00001777-D01P] - Analysis of DNASE2 expression in transfected 293T cell line by DNASE2 polyclonal antibody.Lane 1: DNASE2 transfected lysate(39.60 KDa).Lane 2: Non-transfected lysate.

DNase II alpha Polyclonal Antibody - bs-7652R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Human colon cancer 4% Paraformaldehyde-fixed and paraffin-embedded.\\nAntigen retrieval: Citrate buffer ( 0.01M, pH 6.0 ) boiling bath for 15min; Blocking buffer (normal goat serum 10%) at 37℃ for 20 min;\\nIncubation: Anti-DNase II Polyclonal Antibody, Unconjugated(bs-7652R) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. DAPI(5ug/ml,blue) was used to stain the cell nuclei\\n

Anti-DNASE2 antibody produced in mouse - SAB1405722 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-DNASE2: <B>Cat. No. SAB1405722</B>: Antibody concentration: 10 μg/mL using HeLa cell.
Search more