BHLHE41

Gene Symbol	BHLHE41
Entrez Gene	79365
Alt Symbol	BHLHB3, DEC2, SHARP1, hDEC2
Species	Human
Gene Type	protein-coding
Description	basic helix-loop-helix family, member e41
Other Description	basic helix-loop-helix domain containing, class B, 3|class E basic helix-loop-helix protein 41|differentially expressed in chondrocytes protein 2|enhancer-of-split and hairy-related protein 1
Swissprots	A2I2N8 Q9C0J9
Accessions	ABM64207 EAW96527 EAW96528 Q9C0J9 AB044088 BAB21502 AJ270695 AK303677 BAH14012 AK311258 AW500664 AY665466 AAV54601 AY665467 AAV54602 BC025968 AAH25968 NM_030762 NP_110389
Function	Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity. {ECO:0000269|PubMed:11278948, ECO:0000269|PubMed:14672706, ECO:0000269|PubMed:15193144, ECO:0000269|Pu
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
Tissue Specificity	Highly expressed in skeletal muscle and brain, moderately expressed in pancreas and heart, weakly expressed in placenta, lung, liver and kidney.
Top Pathways	Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Class E basic helix-loop-helix protein 41 (BHLHE41), Human, ELISA Kit - E01C0968 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7244274 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

basic helix-loop-helix family, member e41, ELISA Kit - MBS9332323 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/ml. Range 3.12 ng/ml - 100 ng/ml.

Class E basic helix loop helix protein 41 (BHLHE41), ELISA Kit - MBS7248096 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7228184 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7212574 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7209816 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7209587 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7253625 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7207290 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7236737 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7214282 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7231178 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E basic helix-loop-helix protein 41 (BHLHE41), ELISA Kit - MBS7202008 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human BHLHE41 ELISA Kit - E009547 from Biobool Category ELISA Kit

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9346427 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9348823 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9365768 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9357770 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9349709 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9357877 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9362917 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9363899 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9356534 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Class E Basic Helix-Loop-Helix Protein 41 (BHLHE41), ELISA Kit - MBS9348244 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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