Gene Symbol | ESPL1 |
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Entrez Gene | 9700 |
Alt Symbol | ESP1, SEPA |
Species | Human |
Gene Type | protein-coding |
Description | extra spindle pole bodies homolog 1 (S. cerevisiae) |
Other Description | caspase-like protein ESPL1|extra spindle poles like 1|extra spindle poles-like 1 protein|separin|separin, cysteine protease |
Swissprots | Q14674 |
Accessions | EAW96681 EAW96682 Q14674 AI458447 AK128350 AK299423 BAG61403 AK316135 BAH14506 AW009863 AY455930 AAR18247 BC047603 BC172238 AAI72238 BC172570 AAI72570 BG328178 BP244662 D79987 BAA11482 XM_006719705 XP_006719768 XM_011539024 XP_011537326 XM_011539025 XP_011537327 XR_944842 NM_012291 NP_036423 |
Function | Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. {ECO:0000269|PubMed:10411507, ECO:0000269|PubMed:11509732}. |
Subcellular Location | Cytoplasm. Nucleus. |
Top Pathways | Cell cycle, Oocyte meiosis |
Mouse/Human Phospho-ESPL1 / Separase (Ser801) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1100 from LifeSpan Bioscience
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Mouse/Human ESPL1 / Separase ELISA Kit (Cell-Based ELISA) - LS-F2301 from LifeSpan Bioscience
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SEPARASE Colorimetric Cell-Based ELISA Kit - CB5625 from Assay Biotechnology
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SEPARASE (Phospho-Ser801) Colorimetric Cell-Based ELISA Kit - CBP1079 from Assay Biotechnology
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extra spindle pole bodies homolog 1 (S. cerevisiae) , ELISA Kit - MBS9324618 from MyBioSource
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Human Separin ELISA Kit - EKE55168 from Biomatik
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Human ESPL1 ELISA Kit - E013879 from Biobool
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ESPL1 ELISA Kit (Human) (OKEH03528) - OKEH03528 from Aviva Systems Biology
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Human Separin ELISA Kit - EK3714 from Signalway Antibody
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Separin, ELISA Kit - MBS9427545 from MyBioSource
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Separin, ELISA Kit - MBS2888059 from MyBioSource
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Separin, ELISA Kit - MBS2888060 from MyBioSource
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