ESPL1

Gene Symbol	ESPL1
Entrez Gene	9700
Alt Symbol	ESP1, SEPA
Species	Human
Gene Type	protein-coding
Description	extra spindle pole bodies homolog 1 (S. cerevisiae)
Other Description	caspase-like protein ESPL1|extra spindle poles like 1|extra spindle poles-like 1 protein|separin|separin, cysteine protease
Swissprots	Q14674
Accessions	EAW96681 EAW96682 Q14674 AI458447 AK128350 AK299423 BAG61403 AK316135 BAH14506 AW009863 AY455930 AAR18247 BC047603 BC172238 AAI72238 BC172570 AAI72570 BG328178 BP244662 D79987 BAA11482 XM_006719705 XP_006719768 XM_011539024 XP_011537326 XM_011539025 XP_011537327 XR_944842 NM_012291 NP_036423
Function	Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. {ECO:0000269|PubMed:10411507, ECO:0000269|PubMed:11509732}.
Subcellular Location	Cytoplasm. Nucleus.
Top Pathways	Cell cycle, Oocyte meiosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Separase peptide - ab97944 from Abcam Category Peptide

Human Separase protein fragment - ab153009 from Abcam Category Protein Source Wheat germ Species Human

ESPL1 / Separase Antibody Blocking Peptide - LS-E7316 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Separase Blocking Peptide - BC110-55295PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Separase Blocking Peptide - BC110-55296PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Recombinant Human Separase Protein - H00009700-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Separase Peptide - P1413 from Novus Biologicals Category Peptide Species Human

Phospho-SEPARINS1126-Antibody-Blocking-peptide - BP3247a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Biotinylated-Separase-S1176-Non-phospho-Control-Peptide - SP2071d from Abgent, a WuXi AppTec company Category Peptide Prices $150.00 Sizes 1 mg

Separase-S1176-Non-phospho-Control-Peptide - SP2071c from Abgent, a WuXi AppTec company Category Peptide Prices $132.00 Sizes 1 mg

Biotinylated-Separase-S1176-Phospho-Peptide - SP2071b from Abgent, a WuXi AppTec company Category Peptide Prices $300.00 Sizes 1 mg

Separase-S1176-Phospho-Peptide - SP2071a from Abgent, a WuXi AppTec company Category Peptide Prices $150.00 Sizes 1 mg

Biotinylated-Separase-S801-Non-phospho-Control-Peptide - SP2070d from Abgent, a WuXi AppTec company Category Peptide Prices $150.00 Sizes 1 mg

Separase-S801-Non-phospho-Control-Peptide - SP2070c from Abgent, a WuXi AppTec company Category Peptide Prices $132.00 Sizes 1 mg

Biotinylated-Separase-S801-Phospho-Peptide - SP2070b from Abgent, a WuXi AppTec company Category Peptide Prices $300.00 Sizes 1 mg

Separase-S801-Phospho-Peptide - SP2070a from Abgent, a WuXi AppTec company Category Peptide Prices $150.00 Sizes 1 mg

Biotinylated-Separase-S748-Non-phospho-Control-Peptide - SP2069d from Abgent, a WuXi AppTec company Category Peptide Prices $150.00 Sizes 1 mg

Separase-S748-Non-phospho-Control-Peptide - SP2069c from Abgent, a WuXi AppTec company Category Peptide Prices $132.00 Sizes 1 mg

Biotinylated-Separase-S748-Phospho-Peptide - SP2069b from Abgent, a WuXi AppTec company Category Peptide Prices $300.00 Sizes 1 mg

Separase-S748-Phospho-Peptide - SP2069a from Abgent, a WuXi AppTec company Category Peptide Prices $150.00 Sizes 1 mg

Separin / ESPL1 - H00009700-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Separin / ESPL1 - H00009700-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Separase (pS801) Blocking Peptide - CBP3370 from Cohesion Biosciences Category Peptide Prices $150.00, $450.00 Sizes 1 mg, 5 mg Species Human

Separase (A795) Peptide - AP0374P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Separase (A795) Peptide - BS1710P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

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