ESPL1

Gene Symbol ESPL1
Entrez Gene 9700
Alt Symbol ESP1, SEPA
Species Human
Gene Type protein-coding
Description extra spindle pole bodies homolog 1 (S. cerevisiae)
Other Description caspase-like protein ESPL1|extra spindle poles like 1|extra spindle poles-like 1 protein|separin|separin, cysteine protease
Swissprots Q14674
Accessions EAW96681 EAW96682 Q14674 AI458447 AK128350 AK299423 BAG61403 AK316135 BAH14506 AW009863 AY455930 AAR18247 BC047603 BC172238 AAI72238 BC172570 AAI72570 BG328178 BP244662 D79987 BAA11482 XM_006719705 XP_006719768 XM_011539024 XP_011537326 XM_011539025 XP_011537327 XR_944842 NM_012291 NP_036423
Function Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. {ECO:0000269|PubMed:10411507, ECO:0000269|PubMed:11509732}.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Cell cycle, Oocyte meiosis

Separase CRISPR/Cas9 KO Plasmid (h) - sc-404170 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase HDR Plasmid (h) - sc-404170-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase Double Nickase Plasmid (h) - sc-404170-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase Double Nickase Plasmid (h2) - sc-404170-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase CRISPR Activation Plasmid (h) - sc-404170-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase CRISPR Activation Plasmid (h2) - sc-404170-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase Lentiviral Activation Particles (h) - sc-404170-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase Lentiviral Activation Particles (h2) - sc-404170-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Separase siRNA (h) - sc-72040 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Separase shRNA Plasmid (h) - sc-72040-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Separase shRNA (h) Lentiviral Particles - sc-72040-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Separase RNAi - H00009700-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU005961 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7987 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7987 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ESPL1 siRNA (Human) - CRH6471 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ESPL1 - MBS8225879 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ESPL1(NM_012291.4) - SHG210583 from Creative biogene

Category siRNA
Species Reactivities Human

ESPL1 shRNA Plasmid (Human) - CHH6471 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ESPL1 miRNA 3'UTR clone - MiUTR1H-03311 from Creative biogene

Species Reactivities Human
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