RXRA

Gene Symbol	RXRA
Entrez Gene	6256
Alt Symbol	NR2B1
Species	Human
Gene Type	protein-coding
Description	retinoid X receptor, alpha
Other Description	nuclear receptor subfamily 2 group B member 1|retinoic acid receptor RXR-alpha|retinoid X nuclear receptor alpha
Swissprots	Q2V504 B3KY83 P19793 Q2NL52
Accessions	ABB96254 CBX47611 EAW88122 EAW88123 EAW88124 EAW88125 P19793 AB307705 BAH02296 AF052092 AK090416 BAC03397 AK131081 BAC85131 AK131192 BAG54745 AK131513 BC007925 BC009882 BC031356 BC063827 AAH63827 BC096246 BC110998 AAI10999 BM563384 BP422254 BQ220698 BQ637722 CN391132 EU446653 ABZ92182 HQ692843 ADZ17354 U66306 AAC31116 X52773 CAA36982 NM_001291920 NP_001278849 NM_001291921 NP_001278850 NM_002957 NP_002948
Function	Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXR
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:11915042}.
Tissue Specificity	Highly expressed in liver, also found in lung, kidney and heart.
Top Pathways	Hepatitis C, Non-alcoholic fatty liver disease (NAFLD), PI3K-Akt signaling pathway, Bile secretion, Small cell lung cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse RXTA / RXR-Alpha ELISA Kit (Sandwich ELISA) - LS-F8670 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.067 ng/ml Range 0.156-10 ng/ml

Human RXTA / RXR-Alpha ELISA Kit (Sandwich ELISA) - LS-F9347 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.117 ng/ml Range 0.156-10 ng/ml

Mouse RXTA / RXR-Alpha ELISA Kit (Sandwich ELISA) - LS-F12522 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Retinoic acid receptor RXR-alpha, RXRA, Human, ELISA Kit - E2043h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Retinoid X Receptor Alpha (RXRa), Human, ELISA Kit - SEC043Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.116ng/mL Range 0.312-20ng/mL

RXRA (Human) IP-WB Antibody Pair - H00006256-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

RXRA (Human) IP-WB Antibody Pair - H00006256-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Retinoid X Receptor Alpha, ELISA Kit - MBS105226 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS084789 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS094016 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS052809 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS051277 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS097624 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS078949 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS050792 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS063336 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS052586 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS096363 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS108180 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS075692 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS074169 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS087738 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS066001 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS106714 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Retinoid X Receptor Alpha, ELISA Kit - MBS049134 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more