CES2

Gene Symbol	CES2
Entrez Gene	8824
Alt Symbol	CE-2, CES2A1, PCE-2, iCE
Species	Human
Gene Type	protein-coding
Description	carboxylesterase 2
Other Description	carboxylesterase 2 (intestine, liver)|cocaine esterase|hCE-2|intestinal carboxylesterase; liver carboxylesterase-2|methylumbelliferyl-acetate deacetylase 2
Swissprots	Q16859 O00748 Q5MAB8 Q7Z366 Q8TCP8 Q8IUP4 A8K367
Accessions	AAW29943 EAW83057 EAW83058 EAW83059 O00748 AI601196 AK095522 AK222724 BAD96444 AK290482 BAF83171 AL713761 CAD28531 AM392781 CAL37659 AU137474 BC032095 AAH32095 BC071874 AAH71874 BC098417 AAH98417 BX538086 CAD98009 D50579 BAA23606 DQ893022 ABM83948 DQ896756 ABM87755 U60553 AAB03611 Y09616 CAA70831 XM_011523421 XP_011521723 NM_003869 NP_003860 NM_198061 NP_932327 NR_036684
Function	Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. {ECO:0000269|PubMed:9169443}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000250}.
Tissue Specificity	Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum. {ECO:0000269|PubMed:9144407}.
Top Pathways	Drug metabolism - other enzymes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CES2 ORF Clone(NM_003869.5) - CDCL158607 from Creative Biomart Species Human Accession NM_003869.5

Human CES2 ORF Clone(NM_003869.5) - CDCL158608 from Creative Biomart Species Human Accession NM_003869.5

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone in cloning vector - HG10380-M from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, N-His tag - HG10380-NH from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10380-CH from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid - HG10380-UT from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10380-NF from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10380-NM from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10380-CY from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10380-CF from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10380-NY from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10380-CM from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10380-ANG from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10380-ACR from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10380-ANR from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10380-ACG from Sino Biological Species Human

Human CES2/Carboxylesterase 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10380-M-F from Sino Biological Species Human

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