CES2

Gene Symbol CES2
Entrez Gene 8824
Alt Symbol CE-2, CES2A1, PCE-2, iCE
Species Human
Gene Type protein-coding
Description carboxylesterase 2
Other Description carboxylesterase 2 (intestine, liver)|cocaine esterase|hCE-2|intestinal carboxylesterase; liver carboxylesterase-2|methylumbelliferyl-acetate deacetylase 2
Swissprots Q16859 O00748 Q5MAB8 Q7Z366 Q8TCP8 Q8IUP4 A8K367
Accessions AAW29943 EAW83057 EAW83058 EAW83059 O00748 AI601196 AK095522 AK222724 BAD96444 AK290482 BAF83171 AL713761 CAD28531 AM392781 CAL37659 AU137474 BC032095 AAH32095 BC071874 AAH71874 BC098417 AAH98417 BX538086 CAD98009 D50579 BAA23606 DQ893022 ABM83948 DQ896756 ABM87755 U60553 AAB03611 Y09616 CAA70831 XM_011523421 XP_011521723 NM_003869 NP_003860 NM_198061 NP_932327 NR_036684
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. {ECO:0000269|PubMed:9169443}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000250}.
Tissue Specificity Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum. {ECO:0000269|PubMed:9144407}.
Top Pathways Drug metabolism - other enzymes

CES2 CRISPR/Cas9 KO Plasmid (h) - sc-406052 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 HDR Plasmid (h) - sc-406052-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 Double Nickase Plasmid (h) - sc-406052-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 Double Nickase Plasmid (h2) - sc-406052-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 CRISPR Activation Plasmid (h) - sc-406052-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 CRISPR Activation Plasmid (h2) - sc-406052-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 Lentiviral Activation Particles (h) - sc-406052-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 Lentiviral Activation Particles (h2) - sc-406052-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CES2 siRNA (h) - sc-62098 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CES2 shRNA Plasmid (h) - sc-62098-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CES2 shRNA (h) Lentiviral Particles - sc-62098-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU010091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5986 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5986 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07709 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07709

CES2 siRNA (Human) - CRH5822 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CES2 - MBS8232795 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CES2 (NM_198061.2) - SHH262201 from Creative biogene

Category siRNA
Species Reactivities Human

Human CES2 siRNA - orb266324 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CES2 shRNA Plasmid (Human) - CHH5822 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CES2 miRNA 3'UTR clone - MiUTR3H-07538 from Creative biogene

Species Reactivities Human

CES2 miRNA 3'UTR clone - MiUTR3H-07539 from Creative biogene

Species Reactivities Human
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