CES2

Gene Symbol	CES2
Entrez Gene	8824
Alt Symbol	CE-2, CES2A1, PCE-2, iCE
Species	Human
Gene Type	protein-coding
Description	carboxylesterase 2
Other Description	carboxylesterase 2 (intestine, liver)|cocaine esterase|hCE-2|intestinal carboxylesterase; liver carboxylesterase-2|methylumbelliferyl-acetate deacetylase 2
Swissprots	Q16859 O00748 Q5MAB8 Q7Z366 Q8TCP8 Q8IUP4 A8K367
Accessions	AAW29943 EAW83057 EAW83058 EAW83059 O00748 AI601196 AK095522 AK222724 BAD96444 AK290482 BAF83171 AL713761 CAD28531 AM392781 CAL37659 AU137474 BC032095 AAH32095 BC071874 AAH71874 BC098417 AAH98417 BX538086 CAD98009 D50579 BAA23606 DQ893022 ABM83948 DQ896756 ABM87755 U60553 AAB03611 Y09616 CAA70831 XM_011523421 XP_011521723 NM_003869 NP_003860 NM_198061 NP_932327 NR_036684
Function	Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. {ECO:0000269|PubMed:9169443}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000250}.
Tissue Specificity	Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum. {ECO:0000269|PubMed:9144407}.
Top Pathways	Drug metabolism - other enzymes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CES2 full length protein - ab132595 from Abcam Category Protein Source Wheat germ Species Human

Human CES2 peptide - ab90850 from Abcam Category Peptide

Human CES2 protein fragment - ab152919 from Abcam Category Protein Source Wheat germ Species Human

CES2-Antibody-Center-Blocking-peptide - BP10661c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Caspase 1 recombinant protein - GTX65025 from GeneTex Category Protein Prices $329.00 Sizes 100 unit Source E. coli Species Human

Caspase 1 recombinant protein (Active) - GTX65026 from GeneTex Category Protein Prices $249.00 Sizes 25 unit Source E. coli Species Human

Caspase 1 peptide - GTX27988 from GeneTex Category Peptide Prices $179.00 Sizes 100 μg Species Human

Recombinant Human Carboxylesterase 2/CES2, CF - 5657-CE-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Gln27-Leu559, with a C-terminal 10-His tag

Mouse Carboxylesterase 2 protein - orb83950 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Mouse Species Human

Carboxylesterase 2 Blocking Peptide - 33R-7582 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Carboxylesterase 2 Blocking Peptide - 33R-3874 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CES2 / ICE - H00008824-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CES2 / ICE - H00008824-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CES2 / ICE - H00008824-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CES2 / ICE - H00008824-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CES2 / ICE - H00008824-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CES2 fusion protein - ag2218 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

Recombinant Human CES2, His tagged - CES2-1139H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human CES2 - CES2-1140H from Creative Biomart Category Protein Source baculovirus infected BTI insect cells Species Human

Recombinant Human CES2, MYC/DDK-tagged - CES2-1141H from Creative Biomart Category Protein Source HEK293 cells Species Human

Recombinant Human CES2 - CES2-896H from Creative Biomart Category Protein Source E. coli Species Human

CES2 - PN201445 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

Human CES2 / Carboxylesterase-2 Protein (His Tag) - 10380-H08H-10 from Sino Biological Category Protein Source Human Cells Species Human

Caspase-1, Human, Recombinant, E. coli - 218783 from EMD Millipore Species Human

CES2 Blocking Peptide - CBP2325 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

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