Gene Symbol | ITGA5 |
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Entrez Gene | 3678 |
Alt Symbol | CD49e, FNRA, VLA-5, VLA5A |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
Other Description | CD49 antigen-like family member E|fibronectin receptor subunit alpha|fibronectin receptor, alpha subunit|integrin alpha-5|integrin alpha-F|very late activation protein 5, alpha subunit |
Swissprots | P08648 Q96HA5 |
Accessions | CBX47565 EAW96780 EAW96781 EAW96782 P08648 AK291570 BAF84259 AK304696 BAG65466 AK311051 AK312414 BAG35324 AU133210 AY429549 BC008786 AAH08786 BM787112 BX647780 DQ892690 ABM83616 EU176722 ABW03523 M13918 AAA52467 X06256 CAA29601 NM_002205 NP_002196 |
Function | Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Proteoglycans in cancer, PI3K-Akt signaling pathway, MicroRNAs in cancer, Pertussis, Focal adhesion |
Human Integrin alpha 5 protein fragment - ab151845 from Abcam
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ITGA5/Integrin Alpha 5/CD49e Antibody Blocking Peptide - LS-E1495 from LifeSpan Bioscience
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ITGA5/Integrin Alpha 5/CD49e Antibody Blocking Peptide - LS-E23558 from LifeSpan Bioscience
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ITGA5/Integrin Alpha 5/CD49e Antibody Blocking Peptide - LS-E7871 from LifeSpan Bioscience
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ITGA5/Integrin Alpha 5/CD49e Antibody Blocking Peptide - LS-E7171 from LifeSpan Bioscience
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Recombinant Human Integrin alpha 5/CD49e Protein - H00003678-G01 from Novus Biologicals
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ITGA5-Antibody-Center-Blocking-peptide - BP12204c from Abgent, a WuXi AppTec company
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CD49e-Antibody-C-term-Blocking-Peptide - BP2876b from Abgent, a WuXi AppTec company
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ITGA5-Antibody-C-term-Blocking-peptide - BP5519b from Abgent, a WuXi AppTec company
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Recombinant Human Integrin alpha 5 beta 1, CF - 3230-A5-050 from R&D Systems
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Recombinant Mouse Integrin alpha 5 beta 1, CF - 7728-A5-050 from R&D Systems
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Human ITGA5 flag His tag protein - orb84479 from Biorbyt
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Human Integrin Alpha 5 Protein - abx067272 from Abbexa
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CD49e / ITGA5 - H00003678-G01 from Acris Antibodies
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Integrin Alpha 5 (ITGa5), Human - 20-7623 from ARP American Research Products
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Integrin alpha-5, ITGA5, Human, Recombinant - 19-C478 from ARP American Research Products
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Integrin alpha-5 fusion protein - ag0860 from Proteintech Group
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Recombinant Human ITGA5 Protein - BP001393-C478 from Syd Labs
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Recombinant Human ITGA5, flag & His tagged - ITGA5-4116H from Creative Biomart
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Recombinant Human ITGA5 - ITGA5-101H from Creative Biomart
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Recombinant Human Integrin Alpha 5 Beta 3 Heterodimer Protein - ITGAVB3-101H from Creative Biomart
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Recombinant Human ITGA5, Strep II-His-tagged - ITGA5-5282H from Creative Biomart
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Recombinant Integrin Alpha 5 (ITGa5) - RPB287Hu01 from Uscn Life Science Inc.
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Recombinant Integrin Alpha 5 (ITGa5) - RPB287Mu01 from Uscn Life Science Inc.
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Human ITGA5 & ITGB1 Heterodimer Protein - CT014-H2508H-50 from Sino Biological
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