ITGA5

Gene Symbol	ITGA5
Entrez Gene	3678
Alt Symbol	CD49e, FNRA, VLA-5, VLA5A
Species	Human
Gene Type	protein-coding
Description	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Other Description	CD49 antigen-like family member E|fibronectin receptor subunit alpha|fibronectin receptor, alpha subunit|integrin alpha-5|integrin alpha-F|very late activation protein 5, alpha subunit
Swissprots	P08648 Q96HA5
Accessions	CBX47565 EAW96780 EAW96781 EAW96782 P08648 AK291570 BAF84259 AK304696 BAG65466 AK311051 AK312414 BAG35324 AU133210 AY429549 BC008786 AAH08786 BM787112 BX647780 DQ892690 ABM83616 EU176722 ABW03523 M13918 AAA52467 X06256 CAA29601 NM_002205 NP_002196
Function	Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Proteoglycans in cancer, PI3K-Akt signaling pathway, MicroRNAs in cancer, Pertussis, Focal adhesion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Integrin α5 CRISPR/Cas9 KO Plasmid (h) - sc-400546 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 HDR Plasmid (h) - sc-400546-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 Double Nickase Plasmid (h) - sc-400546-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 Double Nickase Plasmid (h2) - sc-400546-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 CRISPR Activation Plasmid (h) - sc-400546-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 CRISPR Activation Plasmid (h2) - sc-400546-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 Lentiviral Activation Particles (h) - sc-400546-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 Lentiviral Activation Particles (h2) - sc-400546-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Integrin α5 siRNA (h) - sc-29372 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Integrin α5 shRNA Plasmid (h) - sc-29372-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Integrin α5 shRNA (h) Lentiviral Particles - sc-29372-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Integrin alpha 5/CD49e RNAi - H00003678-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU055731 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1534 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1474 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1474 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1534 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07812 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07812

ITGA5 siRNA (Human) - CRH2468 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ITGA5 - MBS8237493 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ITGA5 (NM_002205.2) - SHH321209 from Creative biogene Category siRNA Species Reactivities Human

Human ITGA5 siRNA - orb262970 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ITGA5 shRNA Plasmid (Human) - CHH2468 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ITGA5 miRNA 3'UTR clone - MiUTR1H-05022 from Creative biogene Species Reactivities Human

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