MARCH2

Gene Symbol	MARCH2
Entrez Gene	51257
Alt Symbol	HSPC240, MARCH-II, RNF172
Species	Human
Gene Type	protein-coding
Description	membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
Other Description	E3 ubiquitin-protein ligase MARCH2|RING finger protein 172|membrane-associated RING finger protein 2|membrane-associated RING-CH protein II
Swissprots	Q5H785 Q96B78 Q8N5A3 A6NP10 Q9P0N8
Accessions	EAW68924 Q9P0N8 AB197929 BAD89359 AF151074 AAF36160 AK130163 BC015910 AAH15910 BC032624 AAH32624 BC111388 AAI11389 BI546028 CN363445 DQ582066 XM_006722763 XP_006722826 XM_011528046 XP_011526348 XM_011528047 XP_011526349 NM_001005415 NP_001005415 NM_001005416 NP_001005416 NM_016496 NP_057580
Function	E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6. {ECO:0000269|PubMed:14722266, ECO:0000269|PubMed:15689499, ECO:0000269|PubMed:16428329}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:14722266}; Multi-pass membrane protein {ECO:0000269|PubMed:14722266}. Lysosome membrane {ECO:0000269|PubMed:14722266}; Multi-pass membrane protein {ECO:0000269|PubMed:14722266}. Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity	Broadly expressed. {ECO:0000269|PubMed:14722266}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MARF2-Over-expression-Lysate - LY16504a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

MARCH2 293T Cell Transient Overexpression Lysate(Denatured) - H00051257-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MARCH2 overexpression lysate - LY413937 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MARCH2 overexpression lysate - LY423720 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MARCH2 overexpression lysate - LY423721 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MARCH2 293 Cell Lysate - 406691 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MARCH2 293 Cell Lysate - 409987 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MARCH2 293 Cell Lysate - 409988 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MARCH2 Overexpression Lysate (Native) - NBL1-06998 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MARCH2 Overexpression Lysate (Native) - NBL1-06997 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MARCH2 Over-expression Lysate Product - GWB-8BB531 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MARCH2 Over-expression Lysate Product - GWB-3A4F8A from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

MARCH2 Over-expression Lysate Product - GWB-13DE9F from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

MARCH2 Overexpression Lysate (Native) - NBP2-10746 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MARCH2 Overexpression Lysate (Denatured) - H00051257-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human MARCH2 Knockdown Stable Cell Line - CSC-DC009224 from Creative biogene Category Cell Line Species Human

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