MARCH2

Gene Symbol MARCH2
Entrez Gene 51257
Alt Symbol HSPC240, MARCH-II, RNF172
Species Human
Gene Type protein-coding
Description membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase MARCH2|RING finger protein 172|membrane-associated RING finger protein 2|membrane-associated RING-CH protein II
Swissprots Q5H785 Q96B78 Q8N5A3 A6NP10 Q9P0N8
Accessions EAW68924 Q9P0N8 AB197929 BAD89359 AF151074 AAF36160 AK130163 BC015910 AAH15910 BC032624 AAH32624 BC111388 AAI11389 BI546028 CN363445 DQ582066 XM_006722763 XP_006722826 XM_011528046 XP_011526348 XM_011528047 XP_011526349 NM_001005415 NP_001005415 NM_001005416 NP_001005416 NM_016496 NP_057580
Function E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6. {ECO:0000269|PubMed:14722266, ECO:0000269|PubMed:15689499, ECO:0000269|PubMed:16428329}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:14722266}; Multi-pass membrane protein {ECO:0000269|PubMed:14722266}. Lysosome membrane {ECO:0000269|PubMed:14722266}; Multi-pass membrane protein {ECO:0000269|PubMed:14722266}. Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Broadly expressed. {ECO:0000269|PubMed:14722266}.

MARCH2 (A-12) - sc-131180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MARCH2 (G-12) - sc-131181 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MARCH2 (T-12) - sc-131182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MARCH2 (T-12): sc-131182. Western blot analysis of MARCH2 expression in Jurkat whole cell lysate.

Anti-MARCH2 antibody - ab76397 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MARCH2 antibody (ab76397) at 1 µg/ml + Jurkat cell lysate at 10 µg

Anti-MARCH2 antibody - ab68022 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-MARCH2 antibody (ab68022) at 1/500 dilutionLane 1 : MARCH2 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilutiondeveloped using the ECL technique

Anti-MARCH2 antibody - ab123136 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MARCH2 antibody (ab123136) at 1 µg/ml + Mouse brain lysate at 10 µgdeveloped using the ECL technique

Anti-MARCH2 Antibody (aa147-159) - LS-C55090 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-MARCH2 Antibody - LS-C308894 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MARCH2 Antibody - LS-C308893 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MARCH2 Antibody (aa191-240) - LS-C119929 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using MARCH2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-MARCH2 Antibody (C-Terminus) - LS-C201432 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Esophagus Tumor. MARCH2 antibody dilution 1.0 ug/ml.

Anti-MARCH2 Antibody (aa146-195) IHC-plus™ - LS-B9695 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MARCH2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9695 concentration 10 ug/ml.

MARCH2 Antibody - NBP1-91638 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MARCH2 Antibody [NBP1-91638] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

MARCH2 Antibody - NBP1-60051 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MARCH2 Antibody [NBP1-60051] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

MARCH2 Antibody - NBP2-21582 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MARCH2 Antibody [NBP2-21582] - Sample (30 ug of whole cell lysate) A: HepG2 membrane 12% SDS PAGE gel, diluted at 1:5000.

MARCH2 Antibody - H00051257-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: MARCH2 Antibody [H00051257-B01P] - Analysis of MARCH2 expression in transfected 293T cell line by MARCH2 polyclonal antibody. Lane 1: MARCH2 transfected lysate(19.36 KDa). Lane 2: Non-transfected lysate.

MARCH2 Antibody - H00051257-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: MARCH2 Antibody [H00051257-B01] - analysis of 2-Mar expression in transfected 293T cell line by MARCH2 MaxPab polyclonal antibody (B01). Lane 1: 2-Mar transfected lysate (19.10 KDa). Lane 2: Non-transfected lysate.

MARCH2 Antibody - H00051257-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

MARCH2 Antibody (7F3) - H00051257-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7F3
Western Blot: MARCH2 Antibody (7F3) [H00051257-M04] - Analysis of 2-Mar expression in transfected 293T cell line by MARCH2 monoclonal antibody (M04), clone 7F3. Lane 1: 2-Mar transfected lysatE (19.1 KDa). Lane 2: Non-transfected lysate.

MARCH2 Antibody - NBP1-06052 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

MARCH2 Polyclonal Antibody - bs-9336R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-MARCH2 antibody produced in mouse - SAB1403235 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7F3
<B>Immunoblotting</B><BR/>Monoclonal Anti-40604: <B>Cat. No. SAB1403235</B>: Antibody concentration: 1 μg/mL. Specific band of ~46.1 kDa using immunogen protein lysate.

Anti-MARCH2, C-Terminal antibody produced in rabbit - SAB4502113 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MARCH2, C-Terminal: <B>Cat. No. SAB4502113</B>: Immunohistochemistry analysis of paraffin-embedded human brain tissue using Anti-MARCH2, C-Terminal antibody. Cells on the left were treated with the Anti-MARCH2, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-MARCH2, C-Terminal antibody and the synthesized immunogen peptide.

Anti-MARCH2 antibody produced in mouse - SAB1407467 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MARCH2: <B>Cat. No. SAB1407467</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~19.4 kDa using MARCH2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-MARCH2 (AB1) antibody produced in rabbit - AV43220 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV43220</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type HepG2
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