Gene Symbol | TSLP |
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Entrez Gene | 85480 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | thymic stromal lymphopoietin |
Other Description | - |
Swissprots | Q8IW99 G3XAM8 Q96AU7 Q969D9 |
Accessions | CAL40434 CAL44818 CAV31018 CAX87027 CBX74361 CBX78818 EAW49037 EAW49038 Q969D9 AF338732 AAK60617 AL833421 AY037115 AAK67490 BC016720 AAH16720 BC022894 AAH22894 BC040592 AAH40592 BF245025 BU571002 XM_011543698 XP_011542000 NM_033035 NP_149024 NM_138551 NP_612561 NR_045089 |
Function | Isoform 1: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. {ECO:0000269|PubMed:11418668, ECO:0000269|PubMed:11480573, ECO:0000269|PubMed:17242164}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:11418668}. |
Tissue Specificity | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. {ECO:0000269|PubMed:11480573, ECO:0000269|PubMed:24850429}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
TSLP (FL-159) - sc-33791 from Santa Cruz Biotechnology
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Anti-TSLP antibody - ab47943 from Abcam
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Anti-TSLP antibody - ab188766 from Abcam
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Anti-TSLP antibody - ab184638 from Abcam
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Anti-TSLP antibody (Biotin) - ab84247 from Abcam
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Anti-TSLP Antibody (C-Terminus) IHC-plus⢠- LS-B614 from LifeSpan Bioscience
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Anti-TSLP Antibody (Internal) - LS-C89829 from LifeSpan Bioscience
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Anti-TSLP Antibody (Biotin) - LS-C104690 from LifeSpan Bioscience
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Anti-TSLP Antibody (Biotin) - LS-C106693 from LifeSpan Bioscience
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Anti-TSLP Antibody (clone 15B11.3) - LS-C106915 from LifeSpan Bioscience
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Anti-TSLP Antibody - LS-C189278 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa101-130, AP) - LS-C242238 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa101-130, APC) - LS-C242239 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa101-130, FITC) - LS-C242240 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa101-130, PE) - LS-C242245 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa101-130, Azide-free, HRP) - LS-C247151 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa25-146, Biotin) - LS-C298898 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa25-146, FITC) - LS-C305313 from LifeSpan Bioscience
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Anti-TSLP Antibody - LS-C209274 from LifeSpan Bioscience
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Anti-TSLP Antibody (Biotin) - LS-C209279 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa89-138) - LS-C145989 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa101-130) - LS-C326046 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa100-150) - LS-C148343 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa101-130) - LS-C160256 from LifeSpan Bioscience
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Anti-TSLP Antibody (aa25-146) - LS-C296624 from LifeSpan Bioscience
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