Gene Symbol | TSLP |
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Entrez Gene | 85480 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | thymic stromal lymphopoietin |
Other Description | - |
Swissprots | Q8IW99 G3XAM8 Q96AU7 Q969D9 |
Accessions | CAL40434 CAL44818 CAV31018 CAX87027 CBX74361 CBX78818 EAW49037 EAW49038 Q969D9 AF338732 AAK60617 AL833421 AY037115 AAK67490 BC016720 AAH16720 BC022894 AAH22894 BC040592 AAH40592 BF245025 BU571002 XM_011543698 XP_011542000 NM_033035 NP_149024 NM_138551 NP_612561 NR_045089 |
Function | Isoform 1: Cytokine that induces the release of T-cell- attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. {ECO:0000269|PubMed:11418668, ECO:0000269|PubMed:11480573, ECO:0000269|PubMed:17242164}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:11418668}. |
Tissue Specificity | Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva. {ECO:0000269|PubMed:11480573, ECO:0000269|PubMed:24850429}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Active human TSLP full length protein - ab181964 from Abcam
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Active human TSLP full length protein - ab201363 from Abcam
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Active human TSLP full length protein - ab191777 from Abcam
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Active mouse TSLP full length protein - ab181941 from Abcam
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Human TSLP full length protein - ab194189 from Abcam
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Human TSLP full length protein - ab202263 from Abcam
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Human TSLP protein fragment - ab50020 from Abcam
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TSLP Antibody Blocking Peptide - LS-E3911 from LifeSpan Bioscience
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TSLP Antibody Blocking Peptide - LS-E30302 from LifeSpan Bioscience
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TSLP Antibody Blocking Peptide - LS-E22283 from LifeSpan Bioscience
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TSLP Antibody Blocking Peptide - LS-E30303 from LifeSpan Bioscience
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TSLP Antibody Blocking Peptide - LS-E30304 from LifeSpan Bioscience
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Human TSLP Protein - NBP2-35083 from Novus Biologicals
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TSLP Recombinant Protein - H00085480-P01 from Novus Biologicals
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TSLP Partial Recombinant Protein - H00085480-Q01 from Novus Biologicals
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TSLP Recombinant Protein - P3671 from Novus Biologicals
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TSLP Blocking Peptide - NB110-55234PEP from Novus Biologicals
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TSLP Protein - NBP1-99561 from Novus Biologicals
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TSLP Protein - NBP1-43183 from Novus Biologicals
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TSLP Protein - NBP1-43182 from Novus Biologicals
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TSLP Protein - NBP1-42885 from Novus Biologicals
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TSLP Protein - NBP1-42884 from Novus Biologicals
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TSLP-Antibody-C-term-Blocking-Peptide - BP16103b from Abgent, a WuXi AppTec company
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TSLP (Active) recombinant protein - GTX65453 from GeneTex
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TSLP Recombinant Protein - GTX48249-PRO from GeneTex
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