Gene Symbol | MED17 |
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Entrez Gene | 9440 |
Alt Symbol | CRSP6, CRSP77, DRIP80, TRAP80 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 17 |
Other Description | ARC77|CRSP complex subunit 6|activator-recruited cofactor 77 kDa component|cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa|mediator of RNA polymerase II transcription subunit 17|thyroid hormone receptor-associated protein complex 80 kDa component|transcriptional coactivator CRSP77|vitamin D3 receptor-interacting protein complex 80 kDa component |
Swissprots | Q9HA81 B3KN07 Q9Y660 Q9NVC6 Q9UNP7 Q9Y2W0 |
Accessions | EAW66920 EAW66921 Q9NVC6 AF104254 AAD12723 AF105421 AAD30856 AF117657 AAD22031 AK001674 BAA91827 AK022156 BAB13973 AK023209 BAG51169 AK299702 BAG61603 BC021101 AAH21101 DA506467 DA921529 XM_011543068 XP_011541370 XR_247218 XR_947872 NM_004268 NP_004259 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:16595664}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10198638}. |
CRSP77 (G-17) - sc-12453 from Santa Cruz Biotechnology
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CRSP77 (H-285) - sc-48777 from Santa Cruz Biotechnology
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CRSP77 (S-19) - sc-9428 from Santa Cruz Biotechnology
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CRSP77 (2215C3a) - sc-81238 from Santa Cruz Biotechnology
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Anti-TRAP80 antibody - ab70125 from Abcam
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Anti-TRAP80 antibody - ab124176 from Abcam
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Anti-TRAP80 antibody [2215C3a] - ab51350 from Abcam
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Anti-TRAP80 antibody - C-terminal - ab199887 from Abcam
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Anti-MED17 / TRAP80 Antibody - LS-C79470 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (clone 2215C3a) - LS-C184378 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa331-361, APC) - LS-C237504 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa331-361, Biotin) - LS-C237505 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa331-361, AP) - LS-C237503 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa331-361, PE) - LS-C237511 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa331-361, FITC) - LS-C237506 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa141-190) - LS-C119283 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa331-361, Azide-free, HRP) - LS-C248789 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa156-205) - LS-C29825 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa331-361) - LS-C322937 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa551-652, Azide-free) - LS-C327091 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (aa332-361) - LS-C164117 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (clone 2215C3a) - LS-C342429 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (Val171) - LS-C176952 from LifeSpan Bioscience
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Anti-MED17 / TRAP80 Antibody (clone 4D4) IHC-plus⢠- LS-B6197 from LifeSpan Bioscience
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MED17 Antibody (4D4) - H00009440-M01 from Novus Biologicals
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