Gene Symbol | MED17 |
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Entrez Gene | 9440 |
Alt Symbol | CRSP6, CRSP77, DRIP80, TRAP80 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 17 |
Other Description | ARC77|CRSP complex subunit 6|activator-recruited cofactor 77 kDa component|cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa|mediator of RNA polymerase II transcription subunit 17|thyroid hormone receptor-associated protein complex 80 kDa component|transcriptional coactivator CRSP77|vitamin D3 receptor-interacting protein complex 80 kDa component |
Swissprots | Q9HA81 B3KN07 Q9Y660 Q9NVC6 Q9UNP7 Q9Y2W0 |
Accessions | EAW66920 EAW66921 Q9NVC6 AF104254 AAD12723 AF105421 AAD30856 AF117657 AAD22031 AK001674 BAA91827 AK022156 BAB13973 AK023209 BAG51169 AK299702 BAG61603 BC021101 AAH21101 DA506467 DA921529 XM_011543068 XP_011541370 XR_247218 XR_947872 NM_004268 NP_004259 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:16595664}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10198638}. |
Human TRAP80 full length protein - ab160487 from Abcam
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Human TRAP80 protein fragment - ab160488 from Abcam
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MED17 / TRAP80 Antibody Blocking Peptide - LS-E4018 from LifeSpan Bioscience
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MED17 / TRAP80 Antibody Blocking Peptide - LS-E12102 from LifeSpan Bioscience
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Recombinant Human MED17 Protein - H00009440-Q01 from Novus Biologicals
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MED17 Recombinant Protein - H00009440-P02 from Novus Biologicals
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MED17-Antibody-Center-Blocking-Peptide - BP16245c from Abgent, a WuXi AppTec company
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MED17 - H00009440-P02 from Acris Antibodies
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MED17 - H00009440-Q01-10 from Acris Antibodies
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MED17 - H00009440-Q01-25 from Acris Antibodies
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MED17 fusion protein - Ag24670 from Proteintech Group
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MED17 fusion protein - Ag2057 from Proteintech Group
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Recombinant Human MED17, GST-tagged - MED17-804H from Creative Biomart
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Recombinant Human MED17 - MED17-663H from Creative Biomart
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CRSP77 (V171) Peptide - BS2368P from Bioworld Technology
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Recombinant Human Mediator of RNA polymerase II transcription subunit 17(MED17) - CSB-YP865147HU CSB-EP865147HU CSB-BP865147HU CSB-MP865147HU from Cusabio
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MED17 Peptide, Human - M34GP09362H from Creative Peptides
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MED17 Recombinant Protein Antigen - NBP2-57476PEP from Novus Biologicals
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Mediator of RNA polymerase II transcription subunit 17 (MED17), Recombinant Protein - MBS1374801 from MyBioSource
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