PRKAB1

Gene Symbol	PRKAB1
Entrez Gene	5564
Alt Symbol	AMPK, HAMPKb
Species	Human
Gene Type	protein-coding
Description	protein kinase, AMP-activated, beta 1 non-catalytic subunit
Other Description	5'-AMP-activated protein kinase beta-1 subunit|5'-AMP-activated protein kinase subunit beta-1|AMP-activated protein kinase beta subunit|AMPK beta -1 chain|AMPK beta 1|AMPK subunit beta-1|AMPKb|protein kinase, AMP-activated, noncatalytic, beta-1
Swissprots	Q9Y478 Q9UE20 Q9UEX2 Q9Y6V8 Q9UBV0
Accessions	AAB71326 AAD00625 EAW98151 EAW98152 EAW98153 EAW98154 Q9Y478 AF022116 AAC98897 AJ224515 CAA12024 AK127820 AK301165 BAG62754 AK312495 BAG35397 BC001007 AAH01007 BC001056 AAH01056 BC001823 AAH01823 BC017671 AAH17671 BC018818 BU539177 BX537486 U83994 AAD09237 Y12556 CAA73146 XM_005253909 XP_005253966 NM_006253 NP_006244
Function	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Top Pathways	Non-alcoholic fatty liver disease (NAFLD), Glucagon signaling pathway, AMPK signaling pathway, Oxytocin signaling pathway, Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AMPK beta 1 full length protein - ab132995 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human AMPK beta 1 full length protein - ab132996 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human AMPK beta 1 full length protein - ab136349 from Abcam Category Protein Prices $297.00 Sizes 10 µg Source E. coli Species Human

Human AMPK beta 1 full length protein - ab177266 from Abcam Category Protein Prices $343.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Human AMPK beta 1 peptide - ab91614 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

PRKAB1 / AMPK Beta 1 Antibody Blocking Peptide - LS-E20627 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRKAB1 / AMPK Beta 1 Antibody Blocking Peptide - LS-E8639 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AMPK beta 1 Recombinant Protein - H00005564-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

AMPK beta 1 Recombinant Protein - H00005564-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human AMPK beta 1 Protein - NBP2-23375 from Novus Biologicals Category Protein Prices $269.00 Sizes 10 µg Source E.coli Species Human

AMPK beta 1 Peptide - P2142 from Novus Biologicals Category Peptide Species Human

AMPK-beta-PRKAB1-Antibody-N-term-Blocking-peptide - BP7045a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human PRKAB1 protein - orb169075 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 1 μg, 5 μg, 50 μg Species Human

PRKAB1 Blocking Peptide - 33R-4439 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PRKAB1 protein (His tag) - 80R-2564 from Fitzgerald Category Protein Prices $270.00 Sizes 10 µg Source E.coli

AMPK beta 1 (phospho-Ser182) Blocking Peptide - abx063120 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig

AMPK beta 1 Blocking Peptide - abx062188 from Abbexa Category Peptide Species Human, Mouse, Rat

AMPK beta-1 chain / AMPKb (1-270, His-tag) - AR50610PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

AMPK beta-1 chain / AMPKb (1-270, His-tag) - AR50610PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

AMPK beta-1 chain / AMPKb - H00005564-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AMPK beta-1 chain / AMPKb - H00005564-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AMPK beta-1 chain / AMPKb - H00005564-P02 from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Species Human

AMPK beta-1 chain / AMPKb - H00005564-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

AMPK beta-1 chain / AMPKb - H00005564-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PRKAB1, 1-270aa, Human, His tag, E.coli - 01-P1786 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

Search more